Gynest Cream

• Vaginal dryness and atrophy during menopause: Used for treatment of vaginal dryness, itching and painful sexual intercourse.
• Estrogen deficiency: Used for urogenital symptoms such as vaginal dryness and irritation.
• Before surgery: One dose of cream daily 2 weeks before operation.

Estriol Cream is a Hormone Replacement Therapy (HRT). It contains the female hormone estriol (an estrogen). Estriol induces the normalization of the vaginal epithelium and thus helps to restore the normal microflora and the physiological pH in the vagina. As a result, it increases the resistance of the vaginal epithelial cells to infection and inflammation.

Adult Dose:

• Vulvo-vaginal complaints associated with menopause: Initially: one dose of cream per day for 3 weeks; later: one dose twice a week.
• Before surgery: One dose of cream daily 2 weeks before operation.
• Before Pap smear: Daily application for 7 days as recommended by doctor.

Each dose contains 0.5 mg estriol.

Common Side Effects:

• Local irritation or itching of vagina
• Swelling and increased tenderness of the breasts
• Increased vaginal discharge
• Nausea
• Fluid retention (swollen ankles or feet)

Others: Endometrial cancer, heart attack, stroke, gall bladder disease, skin problems, venous thromboembolism.

Use in Pregnancy: Contraindicated during pregnancy and lactation.

Precautions:

• Patients should keep under doctor's observation for any HRT.
• In case of jaundice, sudden high blood pressure, migraine, severe headache or pregnancy, use should be stopped immediately.
• Children are not allowed to use Estriol cream.
• Tell your doctor if vaginal bleeding occurs.

Overdose: Limited information is available on overdose. Excessive use may cause local irritation.

Storage: Store below 25 degree C. Protect from light and moisture. Keep out of reach of children.