৳ 160/unit
Pack: ৳ 160
৳ 160/unit
Pack: ৳ 160
At a glance
Halobetasol Propionate 0.01% is a super-high potency topical corticosteroid used for plaque psoriasis.
Indications
- Plaque psoriasis - in adults
- Corticosteroid-responsive dermatoses
Pharmacology
Corticosteroids play a role in cellular signaling, immune function, inflammation and protein regulation. Tazarotene is a retinoid prodrug which is converted to its active form, tazarotenic acid, by deesterification. Tazarotenic acid binds to all three members of the retinoic acid receptor (RAR) family: RARα, RARβ and RARγ, but shows relative selectivity for RARβ and RARγ and may modify gene expression.
Dosage
Adult Dose:
- Apply a thin layer to affected areas once daily
- Rub in gently
- Do not exceed approximately 50 g per week
- Can be used for up to 8 weeks
Children (under 18 years):
- Safety and effectiveness not evaluated
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Redness
- Itching
- Swelling
- Burning
- Stinging
- Folliculitis
- Atrophy
- Peeling
- Rash
Rare: Skin ulcer, increased eye pressure, increased sensitivity to sun, skin discoloration
Use in pregnancy
Use in Pregnancy: Contraindicated in pregnancy. Tazarotene is a teratogenic substance.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Contraindicated in pregnancy - Tazarotene is a teratogenic substance
- In females of reproductive potential, obtain negative pregnancy test within 2 weeks prior to initiating treatment
- HPA axis suppression may occur - caution with prolonged use or large areas
- Avoid exposure to sunlight and sunlamps
- Do not use on eczematous skin
Overdose effects
Overdose: Excessive prolonged use may suppress HPA axis - reduce or stop use. Appropriate symptomatic treatment should be given.
Storage conditions
Storage: Store below 30°C, protected from light. Keep out of reach of children.