oshudhkosh

Jonort300mg

OTC
Dosage form:
Capsule
Pack size:
Strip (6 Capsule)

৳ 9/unit

Pack: ৳ 54

At a glance

St. John’s Wort — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

St. John’s Wort is a unique preparation of standardized extract ofSt. John’s Wort , which is widely used as effective herbal medicine in the treatment of depression. The major active constituents ofSt. John’s Wort are hypericin, hyperforin, hyperoside, quercitrin and rich in vitamin C. Jonort possesses antidepressant activity which inhibits re-uptake of neurotransmitters such as serotonin, dopamine, noradrenaline, γ-aminobutyric acid (GABA) and L-glutamate. It has also inhibiting activity of Monoamine oxidase (MAO) and Catechol-O-methyltransferase (COMT). St. John’s Wort is most commonly used to treat for mild to moderate depression and conditions that sometimes go along with depression such as anxiety, tiredness, loss of appetite and insomnia. The main components of __NAME_ are Hypericin and Hyperforin which are responsible for its effects against depression. Although the exact mechanism of action of __NAME_ is unknown but it may inhibit the reuptake of Serotonin and Noradrenaline, inhibit Monoamine Oxidase (MAO), up-regulate Serotonin receptor, and reduce depression.

Indications

St. John’s Wort is used in- Depression Insomnia Seasonal Affective Disorder (SAD) Obsessive Compulsive Disorder (OCD)

Mechanism of action

St. John’s Wort is most commonly used to treat for mild to moderate depression and conditions that sometimes go along with depression such as anxiety, tiredness, loss of appetite and insomnia. The main components of St. John’s Wort are Hypericin and Hyperforin which are responsible for its effects against depression. Although the exact mechanism of action of St. John’s Wort is unknown but it may inhibit the reuptake of Serotonin and Noradrenaline, inhibit Monoamine Oxidase (MAO), up-regulate Serotonin receptor, and reduce depression.

Dosage

Adult Dose: Take one capsule three times per day, or as prescribed by a doctor. Child Dose: Not recommended for children. Renal Dose: It should be used with caution in patients with kidney disease. Dose adjustment of St. John’s Wort may be needed. Please consult your doctor.

Administration

Take St. John’s Wort in the dose and duration as advised by your doctor. Take St. John’s Wort orally with plenty of water. Do not chew, crush or break it.

Missed dose

If you miss a dose of St. John’s Wort, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Sometimes it cause: • Diarrhea • Dry mouth • Constipation • Dizziness

Precautions & warnings

[CAUTION] St. John’s Wort is generally considered safe, it can have some side effects that could impair driving ability.

Contraindications

Contraindicated in patient with a known hypersensitivity to silymarin.

Drug interactions

It interacts with SSRI antidepressants (e.g., fluoxetine, paroxetine), other antidepressants that affect serotonin levels (e.g., nefazodone), and some migraine treatments (e.g., sumatriptan, naratriptan).

Food interactions

[UNSAFE] St. John’s Wort with alcohol is strongly discouraged due to the potential for serious interactions and adverse effects.

Use in pregnancy

[UNSAFE] St. John’s Wort is not recommended for use during pregnancy. Controlled, long-term safety studies are lacking. Please consult your doctor.

Use in lactation

[UNSAFE] Breast-feeding is not recommended while taking this St. John’s Wort due to the potential risk to the infant.

Renal / hepatic impairment

[CONSULT YOUR DOCTOR] St. John’s Wort should be used with caution in patients with kidney disease. Dose adjustment of St. John’s Wort may be needed. Please consult your doctor. [CONSULT YOUR DOCTOR] St. John’s Wort can cause liver damage in some individuals, especially in those with pre-existing liver conditions or who are taking other medications that can affect the liver. Please consult your doctor.

Storage conditions

Keep out of reach of the children. Keep away from direct sunlight; store in a cool and dry place.

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.