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At a glance

Clindamycin 1% Topical is an antibiotic used for the treatment of acne vulgaris, erythrasma, rosacea, periorificial dermatitis, folliculitis, and skin infections.

Indications
  • Acne vulgaris
  • Erythrasma
  • Rosacea
  • Periorificial dermatitis
  • Folliculitis
  • Stasis, chronic lymphedema and familial pemphigus
  • Dermal ulcers
Pharmacology

Clindamycin inhibits protein synthesis by reversibly binding to the 50S subunit of the ribosomal, thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth.

Dosage

Adult Dose (Topical): Apply a thin layer onto affected area twice daily as a 1% preparation.

Pediatric Dose (12 years): Apply a thin layer onto affected area twice daily.

Side effects

Common Side Effects:

  • Skin rash
  • Pruritus
  • Burning or stinging sensation
  • Skin redness
  • Oily skin

Serious Side Effects (Rare): Colitis (including pseudomembranous colitis), anaphylaxis.

Use in pregnancy

[SAFE IF PRESCRIBED] Clindamycin 1% Topical is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Pregnancy Category B.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • You have been prescribed Clindamycin 1% Topical for the treatment of acne. It may take a long time before your acne starts to improve. Be patient and keep using it every day.
  • Wash your skin with a mild cleanser and pat it dry before applying.
  • Do not apply to broken or damaged skin.
  • Avoid contact with your eyes, nose or mouth. Rinse with water if accidental contact occurs.
  • Use with caution in individuals with a history of gastrointestinal disease, particularly colitis.
  • Caution during pregnancy and lactation.
Overdose effects

Excessive application may result in severe irritation. Discontinue use and wait until the skin has recovered. In the event of accidental ingestion, gastrointestinal adverse reactions similar to those seen with systemically administered clindamycin may be seen.

Storage conditions

Store in a cool and dry place, away from light and out of reach of children.

Clindamycin 1% Topical — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.