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At a glance

Lercanidipine Hydrochloride is a medicine used to treat high blood pressure (hypertension). It belongs to the calcium channel blocker class which helps relax blood vessels and reduce blood pressure and the workload of the heart.

Indications
  • Mild to moderate essential hypertension
Pharmacology

Lercanidipine is a selective calcium channel blocker that inhibits calcium influx into vascular smooth muscle, causing vasodilation and reducing total peripheral resistance.

Dosage

Adult Dose (Oral):

  • Initial: 10 mg once daily (on an empty stomach, at least 15 minutes before meals)
  • May increase to 20 mg daily after 2 weeks if needed
  • Elderly: 10 mg once daily, may increase to 20 mg
  • Caution in mild-moderate renal/hepatic dysfunction; doses above 20 mg daily require caution
  • Not recommended in severe hepatic/renal dysfunction
Side effects

Common Side Effects:

  • Dizziness
  • Edema
  • Fatigue
  • Flushing (sense of warmth in face, ears, neck and trunk)
  • Headache
  • Palpitations
  • Asthenia
  • Dyspepsia, nausea, vomiting, epigastric pain, diarrhea
Use in pregnancy

Use in Pregnancy: Lercanidipine may be unsafe during pregnancy. Animal studies have shown harmful effects on the fetus. Consult your doctor.

Precautions & warnings
  • Blood pressure may drop suddenly, especially when first starting; rise slowly from sitting or lying positions
  • For ankle or foot swelling, elevate legs while sitting
  • Avoid driving or activities requiring concentration if you experience dizziness
  • Caution in patients with sick sinus syndrome, left ventricular dysfunction, and ischemic heart disease
  • Consult your doctor during pregnancy and lactation
Overdose effects

No overdose data available; excessive peripheral vasodilation with marked hypotension and reflex tachycardia may occur. Dialysis is not effective.

Storage conditions

Store below 30°C, away from light and moisture; keep out of reach of children.

Lercanidipine Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.