৳ 3.52/unit
Pack: ৳ 3.52
৳ 3.52/unit
Pack: ৳ 3.52
At a glance
Calcium Carbonate is a calcium supplement and antacid used for the treatment of heartburn, indigestion, stomach upset, calcium deficiency, hypocalcemia, and hyperphosphatemia in chronic renal failure. It neutralizes gastric acid and helps replenish calcium deficiency.
Indications
- Heartburn
- Indigestion
- Stomach upset
- Calcium deficiency
- Hypocalcemia
- Hyperphosphatemia in chronic renal failure
- Calcium supplement
- Osteoporosis prevention
- Pregnancy and lactation calcium supplementation
Pharmacology
Calcium Carbonate reacts with gastric acid to produce salt and water. Two grams of calcium carbonate readily bring 100 mL of hydrochloric acid to a pH above 6. Increased gastric pH reduces pepsin activity. Up to 30% of the oral calcium load may be absorbed.
Dosage
Adults (Hyperacidity): 1-2 tablets as needed, up to a maximum of 16 tablets/day. Tablets may be sucked or chewed.
Hyperphosphatemia in chronic renal failure: Initial dose: 2.5 g/day, up to 17 g/day in divided doses.
Calcium supplement (Osteoporosis prevention): 1250-3750 mg Calcium Carbonate (500-1500 mg calcium)/day.
Pregnancy and lactation: 1200-1500 mg calcium/day.
Renal impairment (CrCl <25 mL/min): Dose adjustments may be needed depending on serum calcium levels.
Children: Half the adult dose.
Side effects
Common side effects: Anorexia, nausea, vomiting, constipation, flatulence.
Serious (long-term/high doses): Hypercalcemia, metabolic alkalosis, milk-alkali syndrome, tissue calcification. Gastric hypersecretion and acid rebound may occur with prolonged use.
Hypercalcemia may occur with large doses in chronic renal failure patients.
Use in pregnancy
Safe during pregnancy (Category C). Calcium supplementation and antacid therapy are widely used during pregnancy. 1200-1500 mg calcium/day is recommended.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in renal impairment, hypoparathyroidism, and hypercalcemia-associated diseases.
- Calcium absorption is impaired in achlorhydria; use an alternative calcium salt and take with food.
- Caution in patients with history of kidney stones.
- Contraindicated in calcium renal calculi or history, hypercalcemia, hypophosphatemia, and suspected digoxin toxicity.
- Lactation: Safe; crosses the placenta and appears in breast milk.
Overdose effects
Overdose symptoms: Nausea, vomiting, dry mouth, loss of appetite, stomach cramps, diarrhea, headache, constipation. Severe cases: hypercalcemia, milk-alkali syndrome, tissue calcification.
Storage conditions
Store in a cool, dry place at controlled room temperature. Keep out of reach of children.