৳ 2.50/unit
Pack: ৳ 25
৳ 2.50/unit
Pack: ৳ 25
At a glance
Meclizine Hydrochloride is an antihistamine used for nausea, vomiting, and vertigo associated with motion sickness. It blocks histamine action in the brain to control nausea, vomiting, and balance.
Indications
- Nausea and vomiting associated with motion sickness
- Vertigo associated with diseases affecting the vestibular system
- Radiation sickness
- Prevention of nausea and vomiting associated with emergency contraceptive pill (ECP)
Pharmacology
Meclizine reduces labyrinthine apparatus sensitivity and blocks vomiting signals through CTZ, VC, and other CNS centers.
Dosage
Adult Dose (Oral):
- Motion sickness: 25-50 mg, 1 hour before travel; repeat every 24 hours if needed
- Vertigo: 25-100 mg daily in divided doses; discontinue if no response after 1-2 weeks
- Radiation sickness: 50 mg, 2-12 hours prior to radiation treatment
Children (12 years+): 12.5-50 mg PO, 1 hour before travel; Vertigo: 25-100 mg/day
Side effects
Common Side Effects:
- Drowsiness
- Dry mouth
- Blurred vision (rare)
Use in pregnancy
Use in Pregnancy: Meclizine is generally considered safe during pregnancy (Category B); animal studies have shown low or no adverse effects to the developing baby.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution when driving or doing activities requiring concentration (may cause drowsiness and dizziness)
- Avoid alcohol (may cause excessive drowsiness)
- Caution in asthma, glaucoma, or prostate enlargement
- Consult doctor during pregnancy and lactation
Overdose effects
Overdose may cause extreme excitability, seizures, drowsiness, and hallucinations; supportive and symptomatic treatment; consider dialysis.
Storage conditions
Store in a cool and dry place, away from children.