oshudhkosh

Medroxy Inj150mg/ml

Rx
Dosage form:
Injection
Pack size:
Injection

৳ 48/unit

Pack: ৳ 48

At a glance

Medroxyprogesterone Acetate — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Medroxyprogesterone Acetate similar to the progesterone hormone naturally produced by the body. It helps in regulating the periods, stop irregular bleeding, and for withdrawal bleeding in case of amenorrhea (unusual stopping of menstrual periods). Medroxyprogesterone Acetate should be taken as your doctor's advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include headache, abdominal pain, weakness, and dizziness. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. It may also cause irregular periods, bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently. Before taking this medicine you must let your doctor know if you ever had any problems like bleeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Pregnant and breastfeeding women should not take this medicine. Medroxyprogesterone Acetate is a progestin (female hormone). It works by replacing the natural progesterone hormone that the body is unable to make. This treats painful, irregular or absent menstrual periods. It also prevents an overgrowth of the lining of the uterus in menopausal women taking oestrogen (another female hormone).

Indications

• Abnormal uterine bleeding • Amenorrhea

Mechanism of action

Medroxyprogesterone is a synthetic progestogen which converts the proliferative phase of the endometrium into secretory phase. It has some androgenic and anabolic activities but no oestrogenic effects. Parenteral use leads to inhibition of pituitary gonadotropins, thus preventing follicular maturation and ovulation.

Dosage

Adult Dose: Oral Amenorrhea, Uterine Bleeding Uterine bleeding: 5-10 mg/day PO for 5-10 days; beginning day 16 or 21 of the menstrual cycle; withdrawal bleeding may be expected within 3 to 7 days after discontinuing medroxyprogesterone Amenorrhea, secondary: 5-10 mg/day PO for 5-10 days; may be started at any time; withdrawal bleeding may be expected within 3-7 days after discontinuing medroxyprogesterone Reduction of endometrial hyperplasia: 5 or 10 mg daily for 12 to 14 consecutive days per month, in postmenopausal women receiving daily 0.625 mg conjugated estrogens, either beginning on the 1st day of the cycle or the 16th day of the cycle. Endometriosis: 10 mg three times a day for 90 consecutive days, beginning on the first day of the menstrual cycle Intramuscular Contraception 150 mg deep IM every 3 months The initial injection should be given during the first 5 days after the onset of a normal menstrual period; within 5 days post-partum if not breast-feeding; or if exclusively breast-feeding at or after six weeks post-partum.

Administration

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Medroxyprogesterone Acetate may be taken with or without food, but it is better to take it at a fixed time.

Side effects

Common: • Headache • Abdominal pain • Weakness • Dizziness • Irregular menstrual cycle • Nervousness

Precautions & warnings

[UNSAFE] Medroxyprogesterone Acetate may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Medroxyprogesterone Acetate is used for a wide range of menstrual disorders such as heavy, painful or absent periods, and endometriosis. It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently. Stop taking Medroxyprogesterone Acetate and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, pain on breathing, sudden changes in your vision or hearing, or yellowing of your skin or whites of your eyes. Use a non-hormonal method of contraception such as condoms to prevent pregnancy while you are taking this medication. Do not take Medroxyprogesterone Acetate if you're pregnant or breastfeeding, have unusual vaginal bleeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems.

Contraindications

Thromboembolic disorders; cerebral apoplexy; severe hepatic dysfunction; incomplete abortion, hormone-dependent carcinoma; Undiagnosed vaginal bleeding, Undiagnosed urinary tract bleeding, Known or suspected pregnancy, Undiagnosed breast pathology, Missed abortion, Active thromboembolic disorders, Markedly impaired liver function,

Drug interactions

Aminoglutethimide and enzyme-inducing drugs (e.g. carbamazepine, griseofulvin, phenobarbital, rifampicin, phenytoin) may reduce plasma concentrations leading to reduced efficacy. Additional measures required when medroxyprogesterone is used for contraception during coadministration with these drugs.

Food interactions

[CAUTION] Caution is advised when consuming alcohol with Medroxyprogesterone Acetate. Please consult your doctor.

Use in pregnancy

[UNSAFE] Medroxyprogesterone Acetate is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Use in lactation

[SAFE IF PRESCRIBED] Medroxyprogesterone Acetate is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Nonhormonal contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum

Renal / hepatic impairment

[CONSULT YOUR DOCTOR] There is limited information available on the use of Medroxyprogesterone Acetate in patients with kidney disease. Please consult your doctor. [UNSAFE] Medroxyprogesterone Acetate is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Common questions

How will I use meprate 10mg orally??? Consult your Gynae for this I want to delay my period date so advice me take tab meprate 10 mg OD starting a week prior to the day u dont want bleeding I have irregular periods and after my last period I have been bleeding for past 14 days. Doctor suggested to take meprate for 12 days once daily in night to stop bleeding. But even after taking meprate for past 4 days I'm having spotting and red discharge. What should I do now? Continue with meprate. Consult your if she wants to increase the dose.It's a hormonal tablet. Don't stop in between otherwise the bleeding can start again My periods are 7days late and I m so worried I didn't had sex and I m still virgin so can u suggest me a best tablet which has no side effects and should be safe for me And i would be bleeding fast after having a tablet Take meprate 10 mg twice daily for 5 days.your periods will come in 2-7 days. Pcod no menses for the past 6 months wanna withdrawl Doctor I want to regularize my mense Want to lose weight too You can go on hormonal pills to regularize your cycle. Take care of your diet and do regular exercise for weight loss. Meprate is the tab for withdrawal bleeding any medicine to avoid polycystic overy syndrome i took meprate but after 3 months again become irregular bleeding Regular use of contraceptive pills provide sustained hormonal cover and helps regularise periods. Also weight loss helps a lot with PCOD. My wife have a problem with irregular period. So she consult with doctor and she took meprate tablet. But she is not get periods but now she diagnose that she is pregnant. Is there any problem for that meprate tablet. I can't say for sure, but it should not cause any problem. It's not an indication for termination I have been given meprate from day 17 to day 26 .pleaae let me know whether I can try for a baby this month.will meprate prevent being from pregnant.and shall we take meprate and become pregnant. No it will not prevent but usually it is not given if a couple is trying for pregnancy

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.