৳ 1,200/unit
Pack: ৳ 1,200
৳ 1,200/unit
Pack: ৳ 1,200
At a glance
Meropenem is an antibiotic used for severe bacterial infections of the skin, lungs, stomach, urinary tract, blood, and brain (e.g., meningitis). It kills bacteria by preventing cell wall formation.
Indications
- Pneumonia and nosocomial pneumonia
- Urinary tract infections
- Intra-abdominal infections
- Gynecological infections (endometritis, pelvic inflammatory disease)
- Skin and skin structure infections
- Meningitis
- Septicaemia
- Pulmonary infections in cystic fibrosis
- Empiric treatment for infections in febrile neutropenia
Pharmacology
Meropenem binds to penicillin-binding proteins to inhibit bacterial cell wall synthesis. It demonstrates high stability to serine beta-lactamases and potent bactericidal activity against both gram-positive and gram-negative bacteria.
Dosage
Adult Dose (IV):
- Intra-abdominal infections: 1 g every 8 hours
- Skin infections: 500 mg every 8 hours
- Meningitis/Cystic fibrosis: 2 g every 8 hours
- Susceptible infections: 0.5-1 g every 8 hours
Children (3 months+): 10-40 mg/kg every 8 hours (depending on infection type)
Side effects
Common Side Effects:
- Injection site reactions (pain, swelling, redness)
- Nausea, vomiting
- Headache
- Rash
- Inflammation, thrombophlebitis
- Abdominal pain, diarrhea
Use in pregnancy
Use in Pregnancy: Meropenem is generally considered safe during pregnancy (Category B); animal studies have shown low or no adverse effects to the developing baby.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in penicillin or carbapenem allergy
- Caution in epilepsy or seizure history
- Monitor kidney function and blood counts
- Inform doctor if severe abdominal pain or blood in stools occurs
Overdose effects
Overdose: symptomatic treatment; hemodialysis effective in renal impairment.
Storage conditions
Vial: Store below 30°C in a cool and dry place, away from light and moisture; keep out of reach of children.