Mesala 400

Mesalazine is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It helps to reduce symptoms such as diarrhea, bleeding and stomach pain by reducing inflammation in the bowel. Mesalazine may also be used to treat another type of bowel disease known as Crohn's ileocolitis. It should be taken with food. The tablets should be swallowed whole with water, do not break, crush or chew them. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. The most common side effects of this medicine include nausea, diarrhea, stomach pain, headache, hair loss, itching and flatulence. If these symptoms bother you, do not go away or get worse, tell your doctor. There may be ways of reducing or preventing them. Some people may get a severe allergic reaction which needs urgent medical attention. Contact your doctor immediately if you notice symptoms like swelling of the face, tongue, throat or lips, unusual bleeding, bruising, rash, fever, sore throat or excessive tiredness. Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Your age may also be a factor in deciding whether this medicine is suitable. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. Mesalazine is an aminosalicylate. It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in the intestines. This reduces ulceration, bleeding and stomach pain, and prevents future flare-ups of the disease.

• Ulcerative colitis

Mesalazine is considered to be the active moiety of sulfasalazine. The mechanism of action is uncertain, but may be due to its ability to inhibit local chemical mediators of the inflammatory response especially leukotriene synthesis in the GI mucosa. Action may be topical in terminal ileum and colon rather than systemic.

Adult Dose: Oral Ulcerative colitis Adult: Dose is dependant on preparation and brand used. Acute attack: Initially, up to 4 g daily in 2-4 doses; Maintenance of remission: 2 g daily in 2 divided doses. Child Dose: Oral Ulcerative colitis 5-12 yr: Acute attack: 15-20 mg/kg (max: 1 g) tid; Maintenance of remission: 10 mg/kg (max: 500 mg) 2-3 times daily. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation <20 Avoid.

Use it as advised by your doctor or check the label for directions before use. Mesalazine is to be taken with food.

If you miss a dose of Mesalazine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Flatulence • Hair loss • Headache • Itching • Diarrhea • Nausea • Stomach pain/epigastric pain • Stomach pain

[SAFE] Mesalazine does not usually affect your ability to drive. You have been prescribed Vegaz OD Tablet PR for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis. Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function. Do not take Vegaz OD Tablet PR if you are allergic to aspirin or if you have blood disorders. Do not stop taking the medication suddenly without talking to your doctor.

Hypersensitivity to mesalazine, salicylates and sulfasalazine. Severe impaired renal (CrCl < 20 ml/min) or hepatic function. Children <2 yr.

Do not give with lactulose or other drugs which lower pH for they prevent release of mesalazine. May decrease digoxin absorption.

[CAUTION] Caution is advised when consuming alcohol with Mesalazine. Please consult your doctor.

[CONSULT YOUR DOCTOR] Mesalazine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Mesalazine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. If you are taking Mesalazine, monitor the baby for diarrhea.

[CAUTION] Mesalazine should be used with caution in patients with kidney disease. Dose adjustment of Mesalazine may be needed. Please consult your doctor. Use of Mesalazine is not recommended in patients with severe kidney disease. [CAUTION] Mesalazine should be used with caution in patients with liver disease. Dose adjustment of Mesalazine may be needed. Please consult your doctor.

I have ulcerative colitis since last 15month and now bleeding daily I have used mesalo od tablet continue Take alsarex tablet 2 tablet twice . Avipattikar churan 1 spoon twice. Sootsekhar ras 1 tablet twice with water I m suffering from ulcerative colitis diagnosed since June 2013. Currently using vegaz od 1200mgX3 alongwith calcium n folicacid. During last may 2015 I had flareup and medicated with Budez cr tab and hydrocirtisone enema. Now again after one yr bleeding occurs What shd I do. Whether there is any other risk is dere Needs evaluation for further treatment Will require assessment by gastroenterologist I m suffering frm bronchitis now the problem is going to aggravate perhaps b cos of vegaz od that I was prescribed fr crohns how to controll refer to a physician nearby , depending on your examination findings, you may require medications prophylactically I have ulcerative colitis. Need treatment https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thankshttps://www.1mg.com/otc/jiva-digestol-tablet-otc329948One ?one tablet morning & evening after taking food , use at least 1-2 monthsTake buttermilk in lunch timeAvoid taking milk & milk Product Diagnosed with ulcerative colitis. On medication. Results not consistent. Bleeding in stools. https://www.1mg.com/otc/stop-ibs-tablet-otc3170411-1 Tablet after lunch & dinner, Take at least 1-2 months. Is there any medicine for ulcerative colitis Hi ulcerative colitis can be managed by diet control & some ayurvedic medicine . Permanent Cure for ulcerative colitis https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks I am a ulcerative colitis patient https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks