৳ 3/unit
Pack: ৳ 3
৳ 3/unit
Pack: ৳ 3
At a glance
Flunarizine is a medicine used for the prevention of migraine. It cannot treat an acute attack and will only work to prevent migraines for as long as you continue to take the medicine.
Indications
- Migraine Prophylaxis: Used for prevention of classic (with aura) or common (without aura) migraine.
- Vestibular Vertigo: Used for symptomatic treatment of vestibular vertigo due to diagnosed functional disorder.
- Peripheral Vascular Disease: Used for treatment of peripheral vascular disease.
- Refractory Epilepsy: Used as adjunct therapy for epilepsy resistant to conventional antiepileptic therapy.
Pharmacology
Flunarizine is the difluorinated derivative of cinnarizine. It is a selective calcium channel antagonist. By reducing excessive transmembrane influx of calcium Flunarizine prevents cellular calcium overload. It does not interfere with normal cellular calcium homeostasis. Flunarizine also has some antihistaminic and sedative properties.
Dosage
Adult Dose (Oral):
- Migraine Prophylaxis: 5-10 mg daily at bedtime; <65 years: 10 mg/day; >65 years: 5 mg/day.
- Vertigo and Motion Sickness: 10-20 mg daily (adults); 5 mg daily (children >40 kg).
- Peripheral Vascular Disease: 10 mg twice daily (up to 30 mg/day if required).
- Epileptic Seizure (Add-on): 15-20 mg daily (adults); 5-10 mg daily (children).
Side effects
Common Side Effects: Sleepiness, Weight gain, Muscle pain, Fatigue, Constipation, Nausea, Insomnia, Runny nose, Increased appetite, Depression, Stomach discomfort, Breast pain.
Use in pregnancy
Use in Pregnancy: Information regarding use during pregnancy is not available; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions: It is not known whether Flunarizine alters the ability to drive; do not drive if you experience any symptoms. Not suited for treating an acute migraine attack. Take at night-time before going to bed. May cause sleepiness; don't drive or do anything requiring mental focus until you know how it affects you. Notify doctor if you develop skin rash, muscle aches, tremors, difficulty moving, or abnormal uncontrolled movement. Chronic treatment may give rise to extrapyramidal and depressive symptoms; elderly patients are particularly at risk.
Overdose effects
Overdose: Limited information on overdose; symptomatic treatment.
Storage conditions
Storage: Keep below 30 degree C, away from light and moisture. Keep out of reach of children.