৳ 165/unit
Pack: ৳ 165
৳ 165/unit
Pack: ৳ 165
At a glance
Miltefosine is an antibiotic drug used for the treatment of Kala-azar (Leishmaniasis).
Indications
- Visceral Leishmaniasis (Kala-azar)
- Cutaneous Leishmaniasis
- Mucosal Leishmaniasis
Pharmacology
Miltefosine kills parasites by affecting apoptosis and lipid-dependent cell signalling pathways.
Dosage
Adult Dose (Oral):
- 30-44 kg: 50 mg capsule twice daily (28 days)
- 45 kg or greater: 50 mg capsule three times daily (28 days)
Child Dose: 2.5 mg/kg/day (in 2 divided doses)
Adolescents (≥12 years): 30-44 kg: 100 mg/day; >45 kg: 150 mg/day
Side effects
Common Side Effects (≥2%):
- Nausea and vomiting
- Diarrhea
- Headache
- Decreased appetite
- Dizziness
- Abdominal pain
- Pruritus
- Somnolence
- Elevated transaminases
- Elevated creatinine
Use in pregnancy
Use in Pregnancy: Unsafe. Contraindicated during pregnancy. Perform pregnancy test before treatment.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Contraindicated in pregnancy - perform pregnancy test before treatment
- Use effective contraception during and for 5 months after treatment
- Monitor serum creatinine
- Monitor transaminases and bilirubin
- Encourage fluid intake
- Discontinue if Stevens-Johnson syndrome occurs
Overdose effects
No overdose information available. Doses up to 8 mg/kg used in clinical trials.
Storage conditions
Keep below 30°C temperature away from light and moisture. Keep out of reach of children.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.