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At a glance

Mirogabalin Besylate is a neuropathic pain medication used for diabetic peripheral neuropathic pain and postherpetic neuralgia.

Indications
  • Neuropathic Pain
  • Diabetic Peripheral Neuropathic Pain (DPNP)
  • Postherpetic Neuralgia (PHN)
  • Peripheral Neuropathic Pain (PNP)
Pharmacology

Mirogabalin Besylate binds to α2δ subunits of voltage-gated calcium channels reducing calcium influx and inhibiting neurotransmitter release.

Dosage

Adult Dose (Oral):

  • Initial Dose: 5 mg twice daily
  • Titration: Increase by 5 mg weekly to 15 mg twice daily
  • Maintenance: 10-15 mg twice daily (based on age and symptoms)

Mild Renal Impairment: 5 mg twice daily → 10 mg twice daily

Moderate Renal Impairment: 2.5 mg twice daily → 7.5 mg twice daily

Severe Renal Impairment: 2.5 mg once daily → 7.5 mg once daily

Side effects

Common Side Effects:

  • Somnolence (drowsiness)
  • Dizziness
  • Edema
  • Weight gain
  • Loss of consciousness (rare)
  • Liver dysfunction (rare)
Use in pregnancy

Use in Pregnancy: Safety information not available. Use only if needed.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution while driving (may cause drowsiness and dizziness)
  • Elderly patients caution (risk of falling)
  • Avoid alcohol
  • Dose adjustment needed in renal impairment
Overdose effects

No overdose information available. Symptomatic and supportive treatment.

Storage conditions

Store below 30°C in a dry place away from light and moisture. Keep out of reach of children.

Mirogabalin Besylate — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.