৳ 160/unit
Pack: ৳ 160
৳ 160/unit
Pack: ৳ 160
At a glance
Polyethylene Glycol 3350 + Electrolytes is used for effective relief from constipation, treatment of chronic constipation, and resolving fecal impaction. It exerts an osmotic action in the gut to induce a laxative effect while maintaining electrolyte balance.
Indications
- Constipation
- Treatment of chronic constipation
- Resolving fecal impaction
Pharmacology
Polyethylene Glycol 3350 exerts osmotic action in the gut, retaining water and increasing stool volume which triggers colon motility. Electrolytes are exchanged across the intestinal barrier with serum electrolytes and excreted in fecal water without net gain or loss of sodium, potassium, and water. Sodium chloride maintains electrolyte and fluid balance, potassium chloride plays a role in nerve conduction, and sodium bicarbonate regulates acid-base balance.
Dosage
Adult Dose (Oral):
- Constipation: 25 mL oral solution added to 100 mL water (total 125 mL), once daily; may increase to 2-3 doses daily if needed
- Fecal impaction: 8 doses of 25 mL daily (each in 100 mL water); course not normally exceeding 3 days
Pediatric Dose (>12 years):
- Same as adult
Side effects
Side Effects:
- Electrolyte disturbances (hyperkalemia, hypokalemia)
- Abdominal pain
- Diarrhea
- Headache
- Peripheral edema
- Nausea, abdominal bloating, cramping, flatulence
- High doses may produce excessive stool frequency (especially in elderly)
- Urticaria (allergic reaction)
Use in pregnancy
Use in Pregnancy: No experience during pregnancy; use only if essential.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Impaired cardiovascular function: For fecal impaction, divide dose so no more than two sachets are taken in any one hour
- If symptoms of fluid/electrolyte shifts occur (edema, shortness of breath, increasing fatigue, dehydration, cardiac failure), stop immediately
- Prolonged use with all laxatives is undesirable and may lead to dependence
- Rule out bowel obstruction before initiating (nausea, vomiting, abdominal pain, distention)
Overdose effects
Overdose may cause excessive diarrhea and fluid/electrolyte disturbances; treatment: discontinue drug, fluid replacement, electrolyte monitoring.
Storage conditions
Store in a cool and dry place; keep out of reach of children.