Nab-Xelpac100mg/vial
Rx- Company:
- Beacon Pharmaceuticals PLC
- Dosage form:
- Injection
- Pack size:
- Injection
Save to my medicines
Alert me on price drop
৳ 25,000/unit
Pack: ৳ 25,000
At a glance
Nanoparticle Albumin-Bound (NAB) Paclitaxel is a chemotherapy drug used for metastatic breast cancer, non-small cell lung cancer and pancreatic adenocarcinoma. It prevents depolymerization of cellular microtubules to stop cell division.
Indications
- Metastatic breast cancer (after anthracycline failure)
- Locally advanced or metastatic non-small cell lung cancer (with carboplatin)
- Metastatic adenocarcinoma of the pancreas (with gemcitabine)
Dosage
Breast Cancer: 260 mg/m² IV over 30 min, every 3 weeks
NSCLC: 100 mg/m² IV over 30 min on Days 1, 8, 15 of 21-day cycle + Carboplatin AUC 6
Pancreatic Cancer: 125 mg/m² IV over 30-40 min on Days 1, 8, 15 of 28-day cycle + Gemcitabine 1000 mg/m²
Side effects
Common Side Effects (>10%):
- Alopecia (90%)
- Neutropenia (80%)
- Sensory neuropathy (71%)
- Abnormal EKG (60%)
- Asthenia (47%)
- Myalgia/arthralgia (44%)
- AST increased (39%)
- Anemia (33%)
- Nausea (30%)
- Diarrhea (27%)
- Dyspnea (12%)
Serious: Sepsis, pneumonitis, hypersensitivity reactions
Precautions & warnings
- Causes myelosuppression; monitor CBC
- Sensory neuropathy occurs frequently; may require dose reduction or treatment interruption
- Biliary obstruction or stent are risk factors for severe sepsis
- Increased toxicity in hepatic impairment
- May cause fetal harm; avoid in pregnant women
- Men should not father a child during treatment
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.