৳ 75/unit
Pack: ৳ 75
৳ 75/unit
Pack: ৳ 75
At a glance
Nefopam Hydrochloride is a centrally-acting non-opioid analgesic used for moderate to severe pain. It blocks transmission of pain signals to the brain to decrease pain perception.
Indications
- Acute pain (post-operative, dental, musculo-skeletal and acute traumatic)
- Chronic pain (including cancer pain)
Pharmacology
Nefopam inhibits re-uptake of catecholamines to alter neurotransmitter levels in the CNS, blocking pain signal transmission.
Dosage
Adult Dose (Oral):
- Initial: 2 tablets (60 mg) three times daily
- Range: 30-90 mg three times daily based on response
Elderly Dose: 1 tablet (30 mg) three times daily (initial)
Injection: IM: 20 mg, repeated every 6 hours; slow IV: 20 mg
Side effects
Common Side Effects:
- Nausea
- Nervousness
- Dry mouth
- Lightheadedness
- Urinary retention
- Vomiting
- Blurred vision
- Drowsiness
- Sweating
- Insomnia
- Headache
- Confusion
- Hallucinations
- Tachycardia
- Aggravation of angina
Use in pregnancy
Use in Pregnancy: Not recommended for pregnant women.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in glaucoma and risk of urinary retention
- Caution with concurrent tricyclic antidepressants
- Caution in history of ischaemic heart disease
- Caution while driving (may cause drowsiness and dizziness)
- Avoid alcohol
Overdose effects
Overdose: Neurological symptoms (convulsions, hallucinations, agitation) and cardiovascular response (tachycardia); treat with gastric lavage, emesis, diuresis, activated charcoal, diazepam and beta-blockers.
Storage conditions
Store below 30°C; protect from light & moisture; keep out of reach of children.