৳ 15/unit
Pack: ৳ 225
৳ 15/unit
Pack: ৳ 225
At a glance
Nebivolol + Valsartan is a combination medicine for hypertension. Nebivolol is a beta-blocker that reduces heart rate and dilates blood vessels, while valsartan blocks AT1 receptors to dilate blood vessels and lower blood pressure.
Indications
- Hypertension (high blood pressure)
Pharmacology
Nebivolol blocks β1-adrenergic receptors to reduce heart rate and blood pressure. Valsartan blocks AT1 receptors to prevent vasoconstrictor effects of angiotensin II, resulting in vasodilation and blood pressure reduction.
Dosage
Adult Dose (Oral):
- As initial therapy and for patients not adequately controlled on valsartan 80 mg or nebivolol up to 10 mg: 1 tablet daily (nebivolol 5 mg/valsartan 80 mg)
- Maximum antihypertensive effects attained within 2-4 weeks
Side effects
Side Effects:
- Hypotension
- Hyperkalemia
Use in pregnancy
Use in Pregnancy: Can cause fetal harm when administered to pregnant women; not recommended during pregnancy.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not abruptly discontinue (acute exacerbation of coronary artery disease)
- Monitor glucose in diabetics (beta-blockers may mask hypoglycemia symptoms)
- Monitor renal function and potassium levels
Overdose effects
Overdose - Nebivolol: Bradycardia, hypotension, heart block, heart failure, bronchospasm, hypoglycemia; treat with atropine, IV fluids, vasopressors, glucagon, isoproterenol, digitalis, bronchodilators. Valsartan: Hypotension and tachycardia; not removed by hemodialysis.
Storage conditions
Do not store above 30°C; keep in a dry place; protect from light; keep out of reach of children.