৳ 0.54/unit
Pack: ৳ 54
৳ 0.54/unit
Pack: ৳ 54
At a glance
Nifedipine is a calcium channel blocker used for hypertension and angina prevention. It dilates blood vessels to lower blood pressure and reduce heart workload.
Indications
- Hypertension (high blood pressure)
- Angina pectoris (chest pain)
- Raynaud's phenomenon
- Ischaemic heart disease
- Heart failure
Pharmacology
Nifedipine prevents calcium ion entry into slow channels of cardiac and smooth muscles during depolarisation, producing peripheral and coronary vasodilatation, reducing afterload, peripheral resistance and BP, and increasing coronary blood flow.
Dosage
Adult Dose (Oral):
- Hypertension (immediate-release): 5 mg tid (initial); maintenance: 10-20 mg tid
- Hypertension (extended-release): 10-40 mg bid or 20-90 mg once daily
- Angina: 10 mg tid (initial); maintenance: 10-20 mg tid
- Raynaud's: 5-20 mg tid
Side effects
Common Side Effects:
- Headache
- Flushing
- Ankle swelling
- Dizziness
- Edema
- Fatigue
- Palpitations
Use in pregnancy
Use in Pregnancy: Nifedipine may be unsafe during pregnancy; animal studies show evidence of fetal harm.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not abruptly discontinue (may cause ischaemic pain)
- Monitor blood glucose in diabetic patients
- Caution in renal disease
- Caution while driving (may cause dizziness)
- Avoid alcohol
Overdose effects
Overdose: Hypotension, tachycardia; symptomatic treatment.
Storage conditions
Store below 30°C; protect from light & moisture; keep out of reach of children.