Nilonix 150200mg

Nilotinib is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects. Nilotinib should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Headache, nausea, abdominal pain, and rash are very common side effects of this medicine. If you experience severe diarrhea, consult with your doctor or drink plenty of fluids while on treatment. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels and blood sugar or fat level in the body. Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy. Nilotinib is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

• Blood cancer (Chronic myeloid leukaemia)

Nilotinib is a potent inhibitor of BCR-ABL tyrosine kinase. It binds to and stabilises the inactive conformation of the kinase domain of Abl protein.

Adult Dose: Oral Chronic Myeloid Leukemia (CML), Newly Diagnosed Indicated for initial treatment of newly diagnosed Philadelphia chromosome positive chronic phase chronic myeloid leukemia (Ph+ CP-CML) 300 mg PO q12hr Chronic Myeloid Leukemia (CML), Resistant/Intolerant Indicated for treatment of chronic phase and accelerated pase Ph+ CML in patients resistant to or intolerant to prior therapy that included imatinib 400 mg PO q12hr Hepatic Impairment Newly diagnosed Ph+ CML (chronic phase at 300 mg BID) Mild, moderate, or severe hepatic impairment: Start initial dose at 200 mg BID; if tolerated, may increase to 300 mg BID Resistant or intolerant Ph+ CML (chronic phase or accelerated phase at 400 mg BID) Mild or moderate hepatic impairment: Start initial dose at 300 mg BID; if tolerated, may increase to 400 mg BID Severe hepatic impairment: Start initial dose at 200 mg BID; if tolerated, may increase to 300 mg BID, and then 400 mg BID Child Dose: <18 years old: Not recommended

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Nilotinib is to be taken empty stomach.

If you miss a dose of Nilotinib, skip it and continue with your normal schedule. Do not double the dose.

Common: • Headache • Nausea • Abdominal pain • Rash • Itching • Hair loss • Muscle pain • Fatigue

[UNSAFE] Nilotinib may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Nilotinib is used for the treatment of thyroid cancer. Take it with or without food, preferably at the same time each day. Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools. Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it. Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting. It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools. Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Patients with hypokalaemia, hypomagnaesemia or long QT syndrome. Pregnancy.

Drugs that inhibit gastric acid secretion (e.g. PPIs) may reduce solubility and bioavailability of nilotinib. Potentially Fatal: Concomitant use w/ potent CYP3A4 inhibitors or antiarrhythmics (e.g. amiodarone, disopyramide, quinidine, sotalol, ketoconazole, clarithromycin, atazanavir) and other QT prolonging drugs (e.g. chloroquine, haloperidol, methadone, moxifloxacin, pimozide) may increase nilotinib serum levels and/or increase the risk of QT prolongation. Concomitant use w/ potent CYP3A4 inducers (e.g. rifampcin, phenobarbital, carbamazepine, phenytoin) may decrease nilotinib serum levels.

[SAFE] Consuming alcohol with Nilotinib does not cause any harmful side effects.

[CONSULT YOUR DOCTOR] Nilotinib is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[UNSAFE] Nilotinib is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

[SAFE IF PRESCRIBED] Nilotinib is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nilotinib may not be needed in these patients. Please consult your doctor. [CAUTION] Nilotinib should be used with caution in patients with liver disease. Dose adjustment of Nilotinib may be needed. Please consult your doctor.

She is suffering from chronic myeloid leukemia Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed. Mh mother have blood cancer .recently she got her first induction chemotherapy.in CBC test Immature myeloid cells 18 percent what are indicate.is it serious .is it shown presence of cancer in blood old tell me Dear Mam Greetings from 1mg, The reports shows low hemoglobin and platelet count which can be due to chemotherapy. My frnds are saying that this reports are signs of leukemia Please please help and suggest your opinions and if no what medicine can be taken It&#x27;s curable cancer now a days, so don&#x27;t worry. Get evaluated and find out which Leukaemia you have. Then we will decide for treatment. Is there anything related to blood cancer sir/madam?? For that we need to do bone marrow aspiration, flow cytometry.CBC suggestive of chronic Leukaemia soEven if it is Leukaemia, it will need not to be treated as it is asymptomatic in majority of times. I want to know the symptoms of cancer as I am a smoker Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time. Can blood cancer patients 1st stage do sex with normal girl Sir a blood cancer patients do sex with normal girl can any problem or cause doing with girl or side effect give suggestions Thanks Wait till blood cancer gets cured. Chronic sinusitis about 15 year old nilsin capsule 1 capsule thrice, use shad bindu oil 2-2 mdrops in each nostril Blood Cancer. Is there any medicine to cure blood cancer. Case has to be seen in person