oshudhkosh

Nitrovas0.40%

Rx
Dosage form:
Ointment
Pack size:
30gm tube

৳ 130.49/unit

Pack: ৳ 130.49

At a glance

Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep is used to treat and prevent heart-related chest pain (angina). Angina occurs when the heart muscle is not getting enough blood. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect. Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind. The most common side effect of Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe. Do not use Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anaemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine. Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep is a nitrate. It works by relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain).

Indications

• Angina (heart-related chest pain)

Mechanism of action

Glyceryl trinitrate acts on the enzyme nitric oxide stimulating guanylate cyclase in the vascular smooth muscle cells resulting in the relaxation of smooth muscles. It reduces venous return (preload) and facilitates subendocardial blood flow with redistribution into ischaemic areas. It relieves coronary vasospasm and dilates arterioles reducing afterload. It is useful for relief and prevention of anginal attacks.

Dosage

Adult Dose: Rectal Anal fissure As 0.4% oint: Apply 1.5 mg 12 hrly up to 8 wk applied to the anal canal.

Administration

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Side effects

Common: • Headache

Precautions & warnings

[UNSAFE] Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. It is given via a drip into a vein under the supervision of a doctor. It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists. Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you. Do not consume alcohol while taking Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep as it may cause increased dizziness. Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep as it may cause low blood pressure.

Contraindications

Do not use Glyceryl Trinitrate 0.4% ointment if the patients: are allergic to glyceryl trinitrate or to similar medicines suffer from low blood pressure suffer from heart or blood vessel disorders suffer from closed-angle glaucoma suffer from migraine or recurrent headaches suffer from increased intracranial pressure or high pressure within your skull suffer from anaemia are taking any of the following medicines: sildenafil citrate, tadalafil, vardenafil, medicines for angina or heart pain such as glyceryl trinitrate (GTN), isosorbide dinitrate, amyl or butyl nitrite, medicines for high blood pressure or depression (tricyclic anti-depressants), acetyl cysteine or alteplase

Drug interactions

Enhances bioavailability of dihydroergotamine. Glyceryl trinitrate infusion may prolong pancuronium-induced neuromuscular blockade. May reduce the efficacy of heparin, alteplase and noradrenaline when used together. Efficacy of buccal and sublingual preparations may be reduced by drugs that can cause dry mouth due to decreased dissolution. Aspirin and other NSAIDs may reduce the therapeutic response to glyceryl trinitrate. Potentially Fatal: Orthostatic hypotension may be produced by combined use of calcium channel blockers, antihypertensives, phenothiazines and TCAs. Alcohol may cause severe hypotension and collapse.

Food interactions

[UNSAFE] Consuming alcohol while taking Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Use in pregnancy

[SAFE IF PRESCRIBED] Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Use in lactation

[SAFE IF PRESCRIBED] Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

[SAFE IF PRESCRIBED] Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep may not be needed in these patients. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Glyceryl Trinitrate 0.4% (nitroglycerine) Rectal prep in patients with liver disease. Please consult your doctor.

Common questions

What is heart attack? When heart attack coming? Related to chest pain angina commonly Chest pain headache vetrigo Angina pain Get echo n ECG done Chest pain headache virtigo Angina pain Get ECG n echo done Pain in chest and just behind that portion also. Visit ur physician firstChest pain could be because heart problems I am having chest pain in left side also in left arm Is this pain related to heart attack in any case?? Get ECG n echo done Pain in below heart area Is it gastric ? Or heart related? Get ecg echo tmt done to rule out cardiac problem for gastric can take pantocid dsr empty stomach

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.