oshudhkosh

Nomi2.5mg

Rx
Generic:
Zolmitriptan
Dosage form:
Tablet
Pack size:
Strip (6 Tablet)

৳ 25.17/unit

Pack: ৳ 151.02

At a glance

Zolmitriptan — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Zolmitriptan is used to treat acute migraine attacks. It works by narrowing the blood vessels, thereby relieving migraine headaches and preventing the attack from becoming worse. Zolmitriptan may be taken with or without food. Never skip any doses and try to finish the full course of treatment even if you feel better. In case you missed a dose, take it as soon as you remember it. You should continue to take this medicine as long as the doctor advises and do not stop taking it suddenly. Side effects associated with the use of this medicine include dizziness, dryness in mouth, nausea, sensation of heaviness, warm sensation, tightness sensation, cold sensation, drowsiness, fatigue, and peripheral neuropathy (tingling and numbness of feet and hands). It may cause dizziness, do not drive or operate machinery until you know how this medicine affects you. However, these are temporary and usually resolve on their own in some time. Please consult your doctor in case these do not subside or bother you. Consult your doctor if you develop stomach pain, bloody diarrhea, or worsening high blood pressure while taking Zolmitriptan. Your doctor may advise for regular eye checkups if you have been taking this medicine for a longer time. In case you experience severe chest pain that does not go away or you have wheezing, breathing problems, or any skin rashes, contact the doctor as soon as possible. This medicine may cause an increase in blood pressure, keep a check on your blood pressure while taking this medicine. Migraine headaches occur due to the dilatation (swelling) of blood vessels in the head. Zolmitriptan works by narrowing these blood vessels, thus relieving the migraine headache.

Indications

• Acute migraine headache

Mechanism of action

Zolmitriptan is a selective agonist for serotonin (5HT1 receptors). It relieves migraine by selective constriction of intracranial blood vessels, neuropeptide release inhibition and decreased transmission in the trigeminal pain pathway.

Dosage

Adult Dose: Oral Acute migraine attacks Adult: Initially, 2.5 mg. A 2nd dose may be taken at least 2 hr after the 1st dose if symptoms recur within 24 hr. Max dose: 10 mg in 24 hr. Safety of treating > three headaches in a 30-day period has not been established. Hepatic impairment: Dose reduction may be needed with BP monitoring. Moderate to severe: Max dose: 5 mg/24 hr Renal Dose: After orally dosing zolmitriptan, renal clearance was Reduced by 25% in patients with severe renal impairment (Clcr ?5 ?25mL/min) compared to the normal group (Clcr ?70 mL/min); No significant change in renal clearance was observed in the moderately renally impaired group (Clcr ?26 ?50 mL/min).

Administration

Take this medicine in the dose and duration as advised by your doctor. Do not handle the strips/film with wet hands. Keep it in your mouth but do not swallow it. Zolmitriptan may be taken with or without food, but it is better to take it at a fixed time.

Side effects

Common: • Dizziness • Dryness in mouth • Nausea • Heaviness • Flushing (sense of warmth in the face, ears, neck and trunk) • Tightness sensation • Feeling of cold • Drowsiness • Fatigue • Peripheral neuropathy (tingling and numbness of feet and hand)

Precautions & warnings

[SAFE] Zolmitriptan does not usually affect your ability to drive. You have been prescribed Zolitas ODS 5 Strip for treatment of migraine headaches. Some tips that may help avoid a migraine attack: It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you. Notify your doctor if your migraine occurs more often after starting the medication. Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure. Inform your doctor if you have a history of heart disease or stroke. This medication does not prevent migraine attacks from happening.

Contraindications

Patients at risk of coronary artery disease (post-menopausal women, men >40 yr, hypertension, hypercholesterolemia, smoking, obesity, DM, family history of coronary artery disease) unless evaluated. Wolff-Parkinson-White syndrome; arrhythmias associated with accessory cardiac conduction pathways; previous cerebrovascular accident; uncontrolled or severe hypertension; ischaemic heart disease, history of MI, coronary vasospasm, transient ischaemic attack. Basilar or hemiplegic migraine.

Drug interactions

Increased risk of serotonin syndrome with SSRI, selective serotonin- and norepinephrine-reuptake inhibitors (SNRI). Increased zolmitriptan concentrations with cimetidine, quinolone antibacterials and drugs that inhibit the cytochrome P450 isoenzyme CYP1A2. Potentially Fatal: Increased risk of fatal serotonin syndrome with sibutramine. Increased risk of serotonin syndrome with MAOI and reversible inhibitors of monoamine oxidase type-A (RIMA); do not use zolmitriptan during and for 2 wk after the use of MAOI and RIMAs Do not use within 24 hr of treatment with another 5-HT1 agonist. Increased risk of additive vasoconstriction with ergot alkaloids; zolmitriptan should not be taken within 24 hr of any ergotamine or ergot-type medication.

Food interactions

[UNSAFE] Zolmitriptan may cause excessive drowsiness with alcohol.

Use in pregnancy

[CONSULT YOUR DOCTOR] Zolmitriptan may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Zolmitriptan is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

[CAUTION] Zolmitriptan should be used with caution in patients with severe kidney disease. Dose adjustment of Zolmitriptan may be needed. Please consult your doctor. [CAUTION] Zolmitriptan should be used with caution in patients with liver disease. Dose adjustment of Zolmitriptan may be needed. Please consult your doctor.

Common questions

I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20) Migraine and headache are two different things migraine is primarily headache of one side in symmetrically He has a problem of headache.what is the reason of headache in childMRI nd all reports are normal Migraine, Tension-type headache, Cluster headache and Chronic daily headache are few examples of reason Naxdom 500 uses benifit please Used for acute headache My sister, she gets head ache when she completes her bath or when exposed to cold. When consultanted with an opthalmologist he said there isn't any eye power. Later consulting an other general physician he told that it is due to sinus and migraine and recommend to use half tablet of sinarest and then it decreases. So please advice me What's her problem? It could be migraine or tension type headache I had surgery for DNS 5 years back but still headache persist even after surgery . What should be my next step in treatment of headache ? Headache has many causes. Some causes lies in nose. If headache is not improving after nose surgery nose may not be cause. It can be eye problem, neurological problem or migraine. Consult a neurologist Have acute migraine since last 15 years. The frequency of headache is once a week. The headache occurs on left and right side alternatively. Take nilsin capsule twice,pAthyadi kwath 20 ml twice I am getting so much of headache nearly 10 days with vomthings what tablet I should take pls Acute headache with vomitings requires a neurological examination. Please see a neurologist. Suffering from acute migraine problem, have ectopic kidney TAB HEADSET is to be taken as and when required for headache

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.