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Meclizine Hydrochloride is an antihistamine medicine used to treat nausea, vomiting and vertigo associated with motion sickness. Meclizine Hydrochloride should be taken with or without food, but take it at the same time every day to get the most benefit. If you are travelling, then take it one hour before travelling. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. In case, you have missed any doses than it is better to take the next dose as soon as you remember it. However, you should never take a double dose. Sleepiness is the most common side effect of this medicine. Avoid driving or attention-seeking activity. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. In some cases, it may cause dryness of mouth, so it is advised to drink more water, always carry sugar candy or maintain oral hygiene. Before taking this medicine, let your doctor know if you have glaucoma or have any gastro related issues or have high blood pressure. Inform your doctor if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment. Meclizine Hydrochloride is an antihistaminic medication. It works by blocking the action of histamine, a chemical in the brain that controls nausea, vomiting, and balance. It also makes you sleepy.

• Motion sickness • Vertigo

Meclozine blocks vasopressor response to histamine and has a slight blocking action against acetylcholine. It decreases excitability of the middle ear labyrinth and blocks conduction in the middle ear vestibular-cerebellar pathways.

Adult Dose: Oral Motion sickness Adult: 25-50 mg 1 hr before travelling and repeat 24 hrly if needed. Vertigo and vestibular disorders Adult: 25-100 mg daily in divided doses. Discontinue if there is no response after 1-2 wk of treatment. Nausea and vomiting 25-50 mg daily Radiation sickness: 50 mg administered 2-12 hours prior to radiation treatment. Prevention of nausea and vomiting associated with emergency contraceptive pill (ECP) : 25-50 mg, 1 hour before first ECP dose; repeat if needed in 24 hours. Child Dose: Oral 12 years: 12.5-50 mg PO given 1 hour before travel and then daily PRN Vertigo >12 years: 25-100 mg/day PO in single daily dose or divided q6-12hr

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Meclizine Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Meclizine Hydrochloride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Sleepiness

[UNSAFE] Meclizine Hydrochloride may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Meclizine Hydrochloride can increase the effects of other CNS depressants (alcohol, barbiturates) medicine. If you are using Meclizine Hydrochloride for motion sickness, it should be taken an hour before your travel. Avoid consuming alcohol when taking the Meclizine Hydrochloride, as it may cause excessive sleepiness or drowsiness.

Meclizine Hydrochloride and Pyridoxine Hydrochloride is contraindicated in patients who are hypersensitive to these ingredients.

Additive effects with CNS depressants, neuroleptics, anticholinergics, alcohol.

[UNSAFE] Meclizine Hydrochloride may cause excessive drowsiness with alcohol.

[SAFE IF PRESCRIBED] Meclizine Hydrochloride is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[SAFE IF PRESCRIBED] Meclizine Hydrochloride is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Larger doses or prolonged use of Meclizine Hydrochloride may cause sleepiness and other effects in the baby

[CONSULT YOUR DOCTOR] There is limited information available on the use of Meclizine Hydrochloride in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Meclizine Hydrochloride in patients with liver disease. Please consult your doctor.

While travelling feel like vomiting. When move my head feels uneasy. Checked my eye. As per doctor said vertigo issue.kindly suggest and guide for same likely it is motion sickness; try topamac 25 mg HS andtake tab stugeron 25 mg 30 mins before prolonges travel; pls show 2 neurologist Best and safe medicine for motion sickness Take Ondem 4 mg before u travelOr pheneragan 25 mg if only Ondem doesn't work , because phenargan can make u sleep Vertigo spinning stopped floating sensation is going on Suffering vertigo since 4 months completed repositioning treatment .spinning stopped but floating sensation is continuously going on Taking diligan 25 mg Cognix and clonazepam MRI brain CT brain done blood investigation done findings are Vit b 12 and d2 Defficiency complete treatment for that Rreport of MRI and CT are normal Pl give me advice take ZEVERT PVG THRiCE A DAY To feel giddy sometimes during driving Take tab avomine for motion sickness I feel uneasy during traveling in car i feel vomiting tendency You may have motion sickness. Please see an ENT specialist. Occipital region headache ,neck pain , vertigo, do MRI brain ; start tab topirol 25 mg hs Is there any treatment for motion sickness u can take tab stemetil before travlling Ear in Ringing .Giddiness .Vertigo Tab sturgeon 25 mg twice a day for five days