Nordette-280.15 mg+0.03 mg
Rx- Company:
- One Pharma Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 1/unit
Pack: ৳ 1
At a glance
Ethinylestradiol + Levonorgestrel — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Ethinylestradiol + Levonorgestrel is a medicine used for contraception (to prevent pregnancy) and in the treatment of irregular periods. It helps to prevent release of the egg and its fertilization by the sperm. Ethinylestradiol + Levonorgestrel can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. You should have to start taking the pill on the day one of your menstrual cycle and continue taking it for whole month and start with new pack once the pack get finished. If you experience vomiting with in 4 hours of dose intake, take another tablet. In case you missed your dose and you are late by 12 hours in taking the missed dose, in that case must use a condom while intercourse for a period of 2 days. Nausea, headache, and breast pain are some commonly seen side effects of this medicine. If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them. You might experience spotting or bleeding between menstrual periods or missed periods. Consult with your doctor if this occurs frequently or persists longer. Inform your doctor if you notice swelling and pain in your limbs, shortness of breath, chest pain or changes in vision, as it may be a sign of blood clot. Before taking this medicine, let your doctor know if you smoke and are over 35, or if you have ever had a heart attack or have cancer of uterus/cervix, or vagina. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Do not take the medicine if you are pregnant already or breastfeeding. Ethinylestradiol + Levonorgestrel is a combined oral contraceptive pill. It works by preventing the release of egg (ovulation) and affecting sperm movement in the womb to prevent its union with the egg. It also changes the lining of the womb and renders it unsuitable for pregnancy.
Indications
• Contraception
Mechanism of action
Combination of hormonal contraceptives inhibits ovulation by modulating pituitary secretion of gonadotrophins, luteinising hormone and follicle stimulating hormone through a negative feedback system. They reduce sperm penetration if ovulation does occur by altering the cervical mucus; cause changes in the endometrium which reduce the risk of nidation and may change the tubal transport of the ova through the fallopian tubes.
Dosage
Adult Dose: Oral Contraception Adult The dosage of levonorgestrel and ethinyl estradiol tablets is one white tablet daily for 21 consecutive days, followed by one orange inert tablet daily for 7 consecutive days, according to the prescribed schedule. It is recommended that levonorgestrel and ethinyl estradiol tablets be taken at the same time each day. Hepatic Impairment Do not administer Renal Dose: Renal Impairment Use caution; monitor blood pressure
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ethinylestradiol + Levonorgestrel may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Nausea • Headache • Breast pain • Irregular uterine bleeding
Precautions & warnings
[CONSULT YOUR DOCTOR] It is not known whether Ethinylestradiol + Levonorgestrel alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Your doctor has prescribed Ethinylestradiol + Levonorgestrel to help you prevent pregnancy. It also results in lighter, less painful and more regular menstrual bleeding. Take your pill at the same time every day to help you remember to take it. You may experience menstrual irregularities such as spotting or bleeding between menstrual periods or missed periods. Consult your doctor if this persists. Do not use Ethinylestradiol + Levonorgestrel if you are obese, over 35, smoke, on prolonged bed rest or have a history of blood clots. Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain or changes in vision. These could be symptoms of a blood clot in a vein.
Contraindications
Pregnancy, undiagnosed vaginal bleeding, severe arterial disease (or family history of atherogenic lipid profile); liver adenoma; porphyria; after evacuation of hydatidiform mole; history of breast cancer; hepatic impairment; thrombophloebitis or thromboembolic disorders; breast carcinoma except in selected patients being treated for metastatic disease; oestrogen-dependent tumour; smoking ?40 cigarettes daily; >50 yr; diabetes complications present; BMI >39 kg/m2; migraine with typical focal aura, lasting >72 hr despite treatment or migraine treated with ergot derivatives; BP >160 mmHg systolic and 100 mmHg diastolic; transient ischaemic attacks without headaches; SLE; gallstones; history of haemolytic uraemic syndrome, pruritis during pregnancy; cholestatic jaundice; chorea or deterioration of otosclerosis pemphigoid; breast feeding during 1st 6 mth after delivery.
Drug interactions
CYP3A4 inducers may decrease levels/effects eg aminoglutethimide, carbamazepine, nafcillin, nevirapine, atazanavir, nelfinavir, phenobarbital, phenytoin, lamotrigine, rifamycins, griseofulvin and ritonavir; ampicillin, tetracycline and other antibiotics may reduce efficacy; oestrogens may antagonise anticoagulant effect of coumarins; may inhibit metabolism of prednisolone and ciclosporin; may reduce clearance of alprazolam, chlordiazepoxide, diazepam; may increase clearance of lorazepam, oxazepam, temazepam.
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Ethinylestradiol + Levonorgestrel. Please consult your doctor.
Use in pregnancy
[UNSAFE] Ethinylestradiol + Levonorgestrel is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Use in lactation
[CONSULT YOUR DOCTOR] Ethinylestradiol + Levonorgestrel is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CONSULT YOUR DOCTOR] There is limited information available on the use of Ethinylestradiol + Levonorgestrel in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Ethinylestradiol + Levonorgestrel in patients with liver disease. Please consult your doctor.
Common questions
Contrceptive pills needed for daily use You can take Ovral L for daily use, once a day starting from 3rd of your period. Is Ovral L is safe contaceptive pill to avoid pregnancy, Is there any side effect for this? It is safe you can use after consulting to your female doctor i am taking ovral l and i am having numbness and headache. doctor has adviced to take this course for three months to regulate periods. plz suggest me how to get red of headache due to ovral should i stop taking medicine or i start taking some supplementary food to reduce headache Consult your Dr. If the headache is too much then you should stop the tab. I am taking overal L last 14yers in a gap of 2month per year. There is no any problems at all. But when I discontinue then period with hebby bleeding and pain in nipples. So want to know that may I continue for a lifetime or use any another prosses. Plz suggest. Hi PATIENT to 1mgdoctors. There is no problems continuing Ovral L. But however it would be good to get checked that why is there heavy bleeding and nipple pain without it. I suggest you get an ultrasound scan of pelvis done atleast. OVRAL g tab kyo li jati h. Aur kab li jati h Hi PATIENT to 1mgdoctors. Ovral G is a combined hormonal pill and has many uses. It can be used as a contraceptive, it can be used if a person has irregular periods, of very heavy period flow. It can used in PCOD and also in some dermatological conditions.Its taken daily in a single dose for 21 days. Bulky uterus Adenomyosis feel epain during period & period dateis not fixed every month the date come before five days mo bleeding plot comes Hi PATIENT to 1mgdoctors. Adenomyosis is a uterine problem and would cause pain during and before periods and also irregular bleeding. Try taking combined OCPS like ovral L to control the pain and bleeding. BUT the problem would recur whenever the medicines are stopped. The only complete cure would be to get the uterus removed. All the best. Swelling in face and pain in full body also allergy symptoms on skin like spots and its subside after sometimes.this is happing for last one week. Start cetiz l tablet Can i take ovral l after a break of 2months. I was already on those pills for 1year Now im on my menstrual cycle Its 5th day My. Gynaec advised me to take start from the 5th day of each cycle. Im out of town so could not reach her. Need ur advise on this Yes you can take.