osudhkosh
New
Company•Navana Pharmaceuticals Ltd.

Nortin 25

Rx
Generic: Nortriptyline

৳ 4/unit

Pack: ৳ 40

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At a glance

Nortriptyline is a tricyclic antidepressant used for depression, panic disorder, neuropathic pain and nocturnal enuresis in children. It increases synaptic concentration of serotonin and norepinephrine to stabilize mood.

Indications
  • Depression
  • Panic disorder
  • Neuropathic pain
  • Nocturnal enuresis in children
Pharmacology

Nortriptyline blocks neuronal reuptake of norepinephrine and serotonin to increase their synaptic concentrations in the CNS, improving mood and relieving pain.

Dosage

Adult Dose (Oral):

  • Depression: 75-100 mg/day in 3-4 divided doses; max 150 mg/day in severe depression
  • Elderly: 30-50 mg/day in divided doses
  • Neuropathic pain: 10 mg/day at night, gradually increase to 75 mg/day if needed

Pediatric Dose:

  • Depression (Adolescent): 30-50 mg/day in divided doses
  • Nocturnal enuresis (6-7 yr, 20-25 kg): 10 mg; (8-11 yr, 25-35 kg): 10-20 mg; (>11 yr, 35-54 kg): 25-35 mg (30 min before bedtime, max 3 months)
Side effects

Common Side Effects:

  • Dry mouth
  • Constipation
  • Blurred vision
  • Tremor
  • Sedation
  • Sweating
  • Rashes
  • Behavioral disturbances
  • Increased heart rate
  • Weight gain
  • Difficulty in urination
  • Orthostatic hypotension
Use in pregnancy

Use in Pregnancy: Nortriptyline may be unsafe during pregnancy (Category C); animal studies show evidence of fetal harm.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Do not stop suddenly (withdrawal symptoms may occur)
  • Caution in cardiovascular disease, heart failure or arrhythmias; monitor ECG
  • High doses may produce QTc prolongation
  • Inform doctor if suicidal thoughts or mood changes occur
  • Caution while driving
  • Avoid alcohol
Overdose effects

Overdose: Confusion, restlessness, agitation, vomiting, hyperpyrexia, muscle rigidity, hyperactive reflexes, tachycardia, shock, congestive heart failure, stupor, coma, seizures and respiratory depression; symptomatic treatment.

Storage conditions

Store in a cool and dry place, protect from light; keep out of reach of children.

Nortriptyline — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.