Novefos3gm
Rx- Generic:
- Fosfomycin
- Company:
- Nuvista Pharma Ltd
- Dosage form:
- Powder
- Pack size:
- Sachet
৳ 350/unit
Pack: ৳ 350
At a glance
Fosfomycin — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Fosfomycin belongs to a group of medicines known as antibiotics. It works by killing bacteria, which can cause infections. This medicine is used to treat or prevent infections of the urinary tract. It helps to improve your symptoms and cure the infection. Fosfomycin should be taken on an empty stomach, preferably before bedtime, after emptying the bladder. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back. The most common side effects of this medicine include headache, dizziness, vaginal inflammation and indigestion. Consult your doctor if your condition does not improve even after two to three days or if these side effects bother or worry you. Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. Pregnant or breastfeeding mothers should consult their doctor before using it. Avoid alcohol and caffeinated drinks while using this medicine. It may make you feel sleepy and dizzy. Do not drive if these symptoms occur. Fosfomycin is an antibiotic. It kills the bacteria in the urinary tract by preventing them from forming their own protective covering. It also reduces bacterial attachment to cells lining the bladder. This helps treat or prevent uncomplicated infections of the bladder.
Indications
• Bacterial infections of urinary tract
Mechanism of action
Fosfomycin is a phosphoenolpyruvate (PEP) analogue that irreversibly inhibits enolpyruvate transferase (MurA), which prevents peptidoglycan biosynthesis at an earlier site compared to β-lactams with no cross-resistance with other agents. Thus, it inhibits bacterial cell wall biogenesis & shows bactericidal effects.
Dosage
Adult Dose: Oral Urinary Tract Infection (Acute Cystitis) Acute cystitis caused by E. coli, E. faecalis Women >18 years: 1 sachet (3 g) PO once Males >18 years: 1 sachet (3 g) every 2-3 days for 3 doses Prostatitis 3 g PO every 3 days for 21 days Renal Dose: Renal impairment: No dosage adjustment needed.
Administration
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Fosfomycin is to be taken empty stomach.
Side effects
Common: • Headache • Dizziness • Vaginal inflammation
Precautions & warnings
[UNSAFE] Fosfomycin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Fosfomycin is used to treat and prevent bacterial infections of the urinary tract. Dissolve it in a glass of water and drink immediately, preferably at bedtime, 2 hours after meals (after emptying the bladder). Avoid alcohol and caffeinated drinks, and drink plenty of water while taking Fosfomycin. Diarrhea is a common side effect. Inform your doctor if it does not get better or if you see blood in stools. Fosfomycin may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. Symptoms should get better in 2 to 3 days of the single dose treatment. Inform your doctor if you don't feel better after 2 to 3 days.
Contraindications
Hypersensitivity to fosfomycin.
Drug interactions
Additive or synergistic effect w/ β-lactam antibiotics (e.g. penicillin, ampicillin, cefazolin, carbapenems) and anti-staphylococcal agents (e.g. linezolid, quinupristin/dalfopristin, moxifloxacin). Reduced serum levels w/ drugs which increase GI motility (e.g. metoclopramide).
Food interactions
[SAFE] Consuming alcohol with Fosfomycin does not cause any harmful side effects.
Use in pregnancy
[SAFE IF PRESCRIBED] Fosfomycin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Fosfomycin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[CAUTION] Fosfomycin should be used with caution in patients with kidney disease. Dose adjustment of Fosfomycin may be needed. Please consult your doctor. Use of Fosfomycin is not recommended in patients with severe kidney disease. [CONSULT YOUR DOCTOR] There is limited information available on the use of Fosfomycin in patients with liver disease. Please consult your doctor.
Common questions
Prostrate check up Urinary tract infections Needs antibiotics Meet a urologist Having urine infection since about a month. Took several antibiotics after consultation with doctor but they all show effect only for starting 2 days and then that antibiotic doesn't work. I have taken sporidex 500, zefu cv 500, norflox 400, levofloxin, cefodoxime (each taken for atleast 4-5 days). All work for starting two days then no effect and infection starts to increase. Urine culture report is attached. Kindly suggest medication since problem is increasing day by day. You should consult a urologist and get a few tests done since we need to know the cause of your recurrent urinary tract infections. She has alway Urinary tract infections, and bed wetting problem. How to control over it. Syrup Cystone 10 ml twice a day after food for 2 months. Training to avoid bed wetting to be given 8 mm stone in kidney during pregnancy Nothing needs to be done for this. Take plenty of fluids. It can lead to sudden colicky pain or can predispose to frequent urinary tract infections Repeated urinary tract infections from last 10 year's Please give best treatment complete prevention for urine infection I am suffering from urinary tract infections from last 10 year's, when I use antibiotics then cure temporarily, after some days it will repeat automatically Get urine routine examination n culture n ultrasound kub with PVR Gall bladder/urinary tract stones U will require surgery to remove bladder n right vuj calculus. For gall bladder stones consult general or gastro surgeon Urinary tract infection, painfull send scan copy of lab reports In case of seviour urinary tract infarction treatment In severe UTI you first must get a urine culture done to see for antibiotic sensitivity. Let me know the result so that I can guide you further. All the best.