NVP25mg+50mg
Rx- Company:
- The ACME Laboratories Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 3.01/unit
Pack: ৳ 3.01
At a glance
Meclizine Hydrochloride + Pyridoxine Hydrochloride — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Meclizine Hydrochloride + Pyridoxine Hydrochloride is a combination medicine used in the treatment of vertigo and motion sickness. It prevents the feeling of nausea, vomiting, light-headedness and other symptoms of vertigo. Meclizine Hydrochloride + Pyridoxine Hydrochloride is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine. Common side effects of this medicine include dryness in the mouth, headache, and fatigue. These are usually mild and disappear after a short time. Consult your doctor if they persist. This medicine can also cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your drowsiness. Meclizine Hydrochloride + Pyridoxine Hydrochloride is a combination of two medicines: Meclizine and vitamin B6 (pyridoxine) which treat nausea and vomiting associated with pregnancy. Meclizine is an antihistamine which works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties.
Indications
• Vertigo • Motion sickness
Mechanism of action
Meclozine blocks vasopressor response to histamine and has a slight blocking action against acetylcholine. It decreases excitability of the middle ear labyrinth and blocks conduction in the middle ear vestibular-cerebellar pathways. Pyridoxine is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. It also aids in the release of glycogen stored in the liver and muscles.
Dosage
Adult Dose: Oral Motion sickness Adult: 25-50 mg Meclizine 1 hr before travelling and repeat 24 hrly if needed. Vertigo and vestibular disorders Adult: 25-100 mg Meclizine daily in divided doses. Discontinue if there is no response after 1-2 wk of treatment. Radiation sickness: 50 mg Meclizine administered 2-12 hours prior to radiation treatment. Pyridoxine (vitamin B6) has been shown to be safe and effective in dosages of 50 to 200 mg per day. Child Dose: Oral <12 years: Safety and efficacy not established
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Meclizine Hydrochloride + Pyridoxine Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Dryness in mouth • Allergic reaction • Drowsiness • Headache • Fatigue
Precautions & warnings
[UNSAFE] Meclizine Hydrochloride + Pyridoxine Hydrochloride may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Meclizine Hydrochloride + Pyridoxine Hydrochloride helps treat nausea and vomiting in pregnant women. Take it on an empty stomach with a glass of water. Meclizine Hydrochloride + Pyridoxine Hydrochloride may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you. Do not take Meclizine Hydrochloride + Pyridoxine Hydrochloride with other sedating medications such as those for cough and cold as the combination could worsen dizziness leading to falls or other accidents. Do not take Meclizine Hydrochloride + Pyridoxine Hydrochloride while breastfeeding.
Contraindications
Meclizine Hydrochloride and Pyridoxine Hydrochloride is contraindicated in patients who are hypersensitive to these ingredients.
Drug interactions
Additive effects with CNS depressants, neuroleptics, anticholinergics, alcohol.
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Meclizine Hydrochloride + Pyridoxine Hydrochloride. Please consult your doctor.
Use in pregnancy
[SAFE IF PRESCRIBED] Meclizine Hydrochloride + Pyridoxine Hydrochloride is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Meclizine Hydrochloride + Pyridoxine Hydrochloride is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Larger doses or prolonged use of Meclizine Hydrochloride + Pyridoxine Hydrochloride may cause sleepiness and other effects in the baby
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Meclizine Hydrochloride + Pyridoxine Hydrochloride is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Meclizine Hydrochloride + Pyridoxine Hydrochloride may not be needed in these patients. Please consult your doctor. [SAFE IF PRESCRIBED] Meclizine Hydrochloride + Pyridoxine Hydrochloride is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Meclizine Hydrochloride + Pyridoxine Hydrochloride may not be needed in these patients. Please consult your doctor.
Common questions
Having itching in body & small small piti dazit m tablet twice daily for5 days I have vertigo since three days and I need the help of phisio to prescribe exercises. I am residing at BTM Dollars layout at Bangalore I m from lucknow, you can serch at 1 mg to on you serch location at bangalore, Cerebral palsy for physiotherapy I m Physiotherapist, but i m from lucknow While travelling feel like vomiting. When move my head feels uneasy. Checked my eye. As per doctor said vertigo issue.kindly suggest and guide for same likely it is motion sickness; try topamac 25 mg HS andtake tab stugeron 25 mg 30 mins before prolonges travel; pls show 2 neurologist To feel giddy sometimes during driving Take tab avomine for motion sickness suffering from vertigo since last couple of years and i am taking vertin 24mg with stemetil tab twice a day. but still i m feeling light headed. How is your vertigo. There are different causes of vertigo. Can u describe the duration and timing of vertigo Allergies problem rash in body particularly hand and legs . Allegra-M Tablet ,1 tab once daily in night after dinner for - 1 week I have some serious back pain issue,for about 2 years now,sometimes it eases a bit but worsen more often. I feel the pain severely only after my afternoon sleep. Currently for around last one year having only zerodol th8 tablets to get some relief . Yet for last one week the pain is not easing even after having the tablet twice daily. Can you please help. Stop zerodol tab. Do a m. R. I. First,M. R. I. Of whole spine