৳ 6/unit
Pack: ৳ 6
৳ 6/unit
Pack: ৳ 6
At a glance
Gentamicin is an antibiotic used for various bacterial infections.
Indications
- Bacterial infections
Pharmacology
Gentamicin is an aminoglycoside antibiotic that binds to the 30S ribosomal subunit of susceptible bacteria, disrupting protein synthesis. It affects the integrity of the plasma membrane and the metabolism of RNA, but it's most important effect is inhibition of protein synthesis at the level of the 30s ribosomal subunit.
Dosage
Adult Dose:
- Dosing is individualized - depends on type and severity of infection
- Usually given as IV or IM injection
Renal Impairment: Dose adjustment may be needed
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Hearing loss
- Kidney damage
- Balance disorder
- Injection site pain
Use in pregnancy
Use in Pregnancy: Unsafe during pregnancy. There is definite evidence of risk to the developing baby.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Regular monitoring of kidney function and hearing.
- Avoid dehydration.
- Caution with neuromuscular blocking agents.
Overdose effects
Overdose: Overdose increases risk of ototoxicity and nephrotoxicity. Supportive care should be given.
Storage conditions
Storage: Store below 30°C, away from light. Keep out of reach of children.