৳ 30/unit
Pack: ৳ 300
৳ 30/unit
Pack: ৳ 300
At a glance
Ospemifene is a selective estrogen receptor modulator (SERM) used for treatment of moderate to severe dyspareunia and vaginal dryness, symptoms of vulvar and vaginal atrophy due to menopause.
Indications
- Moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy due to menopause
- Moderate to severe vaginal dryness, a symptom of vulvar and vaginal atrophy due to menopause
Pharmacology
Ospemifene binds to estrogen receptors to produce estrogenic effects in vulvar and vaginal tissues, increasing vaginal epithelial thickness and relieving vaginal dryness and dyspareunia.
Dosage
Adult Dose (Oral):
- Dyspareunia: 60 mg tablet with food once daily
- Vaginal dryness: 60 mg tablet with food once daily
Side effects
Side Effects:
- Hot flush
- Vaginal discharge
- Muscle spasms
- Hyperhidrosis
- Vascular disorders
- Cardiovascular disorders
Use in pregnancy
Use in Pregnancy: Ospemifene is highly unsafe during pregnancy; definite evidence of severe fetal harm. Completely contraindicated.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Risk of stroke and MI
- Risk of DVT and PE
- Risk of endometrial cancer (agonistic effect on endometrium)
- Do not use in patients with history of breast cancer
- Discontinue 4-6 weeks before surgery
Overdose effects
Limited information on overdose; symptomatic treatment.
Storage conditions
Keep below 30°C; protect from light & moisture; keep out of reach of children.