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At a glance

Pancreatin is a pancreatic enzyme supplement used for chronic pancreatitis, cystic fibrosis, pancreatectomy, gastrectomy and other conditions associated with pancreatic insufficiency.

Indications
  • Chronic pancreatitis
  • Cystic fibrosis/Mucoviscidosis
  • Following partial or complete pancreatectomy
  • Total gastrectomy
  • Steatorrhea
  • Somatostatinoma
  • Celiac disease
  • Other conditions associated with pancreatic insufficiency
Pharmacology

Pancreatin contains amylase, protease and lipase enzymes which hydrolyze dietary starch, protein and fat to aid nutrient absorption.

Dosage

Adult Dose (Oral):

  • 2-3 tablets with meals (with little water)
Side effects

Common Side Effects:

  • Nausea
  • Vomiting
  • Abdominal discomfort
  • Buccal and perianal soreness (in infants)
  • Hypersensitivity reactions (sneezing, lacrimation, skin rash)
Use in pregnancy

Use in Pregnancy: Pancreatin may be unsafe during pregnancy; use only if clearly needed.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in patients allergic to animal protein
  • Do not use concurrently with antacids
  • Inform doctor if history of gout, asthma or allergies
  • Monitor blood sugar in diabetic patients
Overdose effects

Excessive dosage may produce laxative effect; systemic toxicity does not occur; very high doses may cause hyperuricaemia and hyperuricosuria.

Storage conditions

Store in a cool and dry place, protected from light; keep out of reach of children.

Pancreatin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.