৳ 70.80/unit
৳ 70.80/unit
Description
PDS 1000 ml is a dialysis solution manufactured by OSL Pharma Limited in Bangladesh. Its active ingredient is Peritoneal Dialysis Solutions.
Indications
This is used for dialysis of peritoneum.
Contraindications
Patients with excessive obesity and in pregnancy.
Composition
- Each 100 ml of solution contains-
- Calcium Chloride 22 mg
- Potassium Chloride 22 mg
- Dextrose Anhydrous 1.5 gm
- Magnessium Chloride 15.2 mg
- Sodium Acetate 476 mg
- Sodium Chloride 556 mg
Pharmacology
Calcium chloride
is used to prevent or treat negative calcium balance. It also regulates action potential excitation threshold to facilitate nerve and muscle performance.
Potassium chloride
is a major cation of the intracellular fluid. It plays an active role in the conduction of nerve impulses in the heart, brain and skeletal muscle; contraction of cardiac skeletal and smooth muscles; maintenance of normal renal function, acid-base balance, carbohydrate metabolism and gastric secretion.
Sodium chloride
is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives.
Sodium lactate
is a sterile, nonpyrogenic solution that is used for fluid and electrolyte replenishment. It has metabolic alkalinising ability and is capable of inducing diuresis depending on the clinical condition of the patient.
Dextrose
is a monosaccharide that is used as a source of calories and water for hydration. It helps to reduce loss of body protein and nitrogen. It also promotes glycogen deposition in the liver. When used with insulin, it stimulates the uptake of potassium by cells, especially in muscle tissue, thus lowering serum potassium levels.
Dosage & Administration
In case of intermittent peritoneal dialysis (IPD): 2 liters solution is instill into the abdominal cavity over a period of 1 hour then drained from the cavity.
The exchange should be continued for 8-36 hours.
Interaction
There are no known drug interactions and none well documented.
Side Effects
During dialysis amino acids and water soluble vitamins may be lost. Fluid and electrolyte imbalance, hypovolemia, hypotension or muscle cramping may occur.
Pregnancy & Lactation
Category - Not Classified. FDA has not yet classified the drug into a specified pregnancy category
Precautions & Warnings
It is used for peritoneal dialysis purposes only.
Therapeutic Class
Peritoneal dialysis solution
Disclaimer: This information is for reference only. Always consult a registered physician before taking any medicine.
At a glance
Peritoneal Dialysis Solutions are used for dialysis of the peritoneum. It is a combination of Calcium Chloride, Potassium Chloride, Dextrose Anhydrous, Magnesium Chloride, Sodium Acetate, and Sodium Chloride to maintain electrolyte and fluid balance.
Indications
- Dialysis of the peritoneum
Pharmacology
Peritoneal Dialysis Solutions maintain electrolyte and fluid balance during peritoneal dialysis. Calcium chloride prevents negative calcium balance, potassium chloride is involved in nerve impulse conduction and muscle contraction, sodium chloride maintains electrolyte and fluid balance, and dextrose provides calories and water.
Dosage
Adult Dose (Intraperitoneal):
- Intermittent Peritoneal Dialysis (IPD): 2 liters solution is instilled into the abdominal cavity over 1 hour, then drained
- Exchange should be continued for 8-36 hours
Side effects
Side Effects:
- Loss of amino acids and water-soluble vitamins during dialysis
- Fluid and electrolyte imbalance
- Hypovolemia
- Hypotension
- Muscle cramping
Use in pregnancy
Use in Pregnancy: FDA has not yet classified into a specific pregnancy category; contraindicated in pregnancy.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- For peritoneal dialysis use only
- Contraindicated in excessive obesity and pregnancy
Overdose effects
No overdose information available; consult your doctor if overused.
Storage conditions
Store in a cool and dry place; keep out of reach of children.