oshudhkosh

Pegneufil6mg/0.6ml

Rx
Dosage form:
Injection
Pack size:
Injection

৳ 20,300/unit

Pack: ৳ 20,300

At a glance

Pegfilgrastim — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Pegfilgrastim is used to prevent infections after chemotherapy. It is a growth factor that stimulates bone marrow to produce white blood cells. These cells protect the body against infections. Pegfilgrastim is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked for regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine. The most common side effects of this medicine include bone pain, joint pain, headache, nausea, and muscle pain. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, shortness of breath, sore throat and swelling around face or neck. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You must avoid driving or attention-seeking activity if you experience dizziness after taking this medicine. Pegfilgrastim is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

Indications

• Infections after chemotherapy

Mechanism of action

Pegfilgrastim is a covalent conjugate of filgrastim and monomethoxypolyethyleneglycol (PEG). It is a colony-stimulating factor which binds to specific cell surface receptors of haematopoietic cells, thereby stimulating proliferation, differentiation, commitment, and end cell functional activation. Pegfilgrastim has delayed renal clearance and prolonged half-life relative to filgrastim as a result of conjugation with PEG.

Dosage

Adult Dose: Subcutaneous Chemotherapy-induced neutropenia, Myelosuppressive Chemotherapy Adjunct Indicated to decrease incidence of infection in patients with non-myeloid malignancies receiving myelosuppressive chemotherapy assoc with febrile neutropenia Adult: 6 mg as a single dose for each chemotherapy cycle, given at least 24 hr after cytotoxic chemotherapy. Child Dose: Subcutaneous Prevention of Chemotherapy Induced Neutropenia 45kg: 6 mg SC once per chemotherapy cycle; do not administer in the period 14 days before and 24 hr after administration of cytotoxic chemotherapy

Administration

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Missed dose

If you miss a dose of Pegfilgrastim, please consult your doctor.

Side effects

Common: • Bone pain • Joint pain • Headache • Nausea • Low blood platelets • Muscle pain • Back pain • Pain in extremity • Injection site pain

Precautions & warnings

[SAFE] Pegfilgrastim does not usually affect your ability to drive. Pegfilgrastim reduces the risk of infection in people treated with chemotherapy. It is usually given as a daily injection into the tissue just under the skin or into the vein. You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant. Store it in the refrigerator, protect it from light, and don't shake it. For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it. Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away. Use caution while driving or doing anything that requires concentration as Pegfilgrastim may cause dizziness. Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine. Stop taking Pegfilgrastim and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Contraindications

Hypersensitivity to Pegfilgrastim or filgrastim; or to any ingredients in the formulation.

Drug interactions

Colony-stimulating factors such as Pegfilgrastim should not be given at the same time as cytotoxic chemotherapy due to the increased risk of myelosuppression.

Food interactions

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Pegfilgrastim. Please consult your doctor.

Use in pregnancy

[CONSULT YOUR DOCTOR] Pegfilgrastim may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Use in lactation

[SAFE IF PRESCRIBED] Pegfilgrastim is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Renal / hepatic impairment

[SAFE IF PRESCRIBED] Pegfilgrastim is safe to use in patients with kidney disease. No dose adjustment of Pegfilgrastim is recommended. [CONSULT YOUR DOCTOR] There is limited information available on the use of Pegfilgrastim in patients with liver disease. Please consult your doctor.

Common questions

Plz check the report and reply She is my wife report one of hospital where operated the tumot operation and one of from delhi srl and last one from tmh mumbai After the diagnosis docror advice rediation now 1 st rediation therapy is finished and doctor giving now nublast 250mg tab So plz check the report and tell me as per the tata memorial final report what is the condition for patient She can live normal life or she can dead in ahead Doctor tells with my family she can live with treatment more than 1 to 2 years Is it right or wrong You are on right treatmentAfter completion of radiation therapy you need to take chemotherapyThat tablet is the chemotherapy What is symptomatic after chemotherapy for metastatic spine Back pain is main symptom which you can get after disease progression My wife is pregnant but my consulting gynaecologist is injecting Ovigyn 5000. Can I know whats the benefit of this injection. As she is already pregnant These infections help in stabilising an early pregnancy and avoids chances of miscarriage. What would be the best treatment for this disease. As i am very confused about doctor's advice. Some said to start chemo 6 cycles without even pet scan. Doctor from hcg Bangalore advised for radiation for 28 set. But doctor's from Bangalore Baptist hospital advised for 3 cycle of chemo therapy finally i did the pet scan and tomorrow have a appointment with the doctor from Baptist hospital. Ideal treatment for these tumor would be chemotherapy along with radiation therapy, but your patient has fistula after surgery so radiation would not be possible, so ahead with chemotherapy. You can have 4 to 6 cycles. cancer patient want radiotherapy after 4 chemotherapy please tell best centet It's in Mumbai Is Radiotherapy necessary for breast Cancer After 6 cycle of chemotherapy But for not all cases Treatment for oral cancers are Surgery Radiotherapy And Chemotherapy My mother have lung cancer adenocarcinoma spread in bone also. After six chemotherapy lung cancer burn out diseases.but in bone not result. First eighth chemotherapy zometa . Last two chemotherapy give them xgeva120 . Can bone cancer cure? No cure for bone

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.