Pemeta100mg/ml
Rx- Generic:
- Pemetrexed
- Company:
- Drug International Ltd.
- Dosage form:
- Injection
- Pack size:
- Injection
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৳ 4,500/unit
Pack: ৳ 4,500
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At a glance
Pemetrexed is a folate analog metabolic inhibitor used for the treatment of non-squamous non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma.
Indications
- Non-squamous Non-Small Cell Lung Cancer (NSCLC)
- Malignant Pleural Mesothelioma
Dosage
Adult Dose (Intravenous):
- NSCLC (with Pembrolizumab and platinum): 500 mg/m² on Day 1 every 21 days for 4 cycles
- NSCLC (with Cisplatin): 500 mg/m² on Day 1 every 21 days for up to 6 cycles
- NSCLC (maintenance): 500 mg/m² on Day 1 every 21 days
- Mesothelioma (with Cisplatin): 500 mg/m² on Day 1 every 21 days
- Requires creatinine clearance ≥45 mL/min
Side effects
Side Effects:
- Myelosuppression (neutropenia, thrombocytopenia, anemia)
- Renal failure
- Bullous and exfoliative skin toxicity (SJS/TEN)
- Interstitial pneumonitis
- Radiation recall
Precautions & warnings
- Vitamin supplementation (folic acid and vitamin B12) must be initiated before first dose and continued for 21 days after last dose; increased myelosuppression risk without supplementation
- Withhold if creatinine clearance <45 mL/min
- Permanently discontinue for severe bullous/exfoliative skin toxicity
- Permanently discontinue if pneumonitis is confirmed
- Permanently discontinue for radiation recall
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.