Penvik FORTE250mg/5ml

• Ear, nose, and throat infections (tonsillitis, pharyngitis, laryngitis, otitis media, sinusitis)
• Lower respiratory tract infections (bronchitis, pneumonia, bronchopneumonia)
• Group A beta-hemolytic streptococcal infections (scarlet fever, erysipelas, rheumatic fever)
• Skin infections (pyodermia, furunculosis, phlegmon, erysipeloid, erythema migrans)
• Bacterial lymphadenitis and lymphangitis
• Infections of the buccal cavity, gums, or jaws
• Prophylaxis of scarlet fever
• Prevention of rheumatic fever recurrences
• Prophylaxis of infection after dental and oral surgical procedures in high-risk patients

Adult Dose (Oral):

• General infections: 250-500 mg every 6 hours
• Rheumatic fever prophylaxis: 250 mg twice daily
• Streptococcal infections (scarlet fever, erysipelas): 125-250 mg every 6-8 hours for 10 days
• Pneumococcal infections (otitis media): 250-500 mg every 6 hours until afebrile for at least 2 days
• Fusospirochetosis/Staphylococcal infections: 250-500 mg every 6-8 hours

Pediatric Dose (Oral):

• Children: 25-50 mg/kg/day every 6 hours
• Children (>1 year): 125-250 mg every 6 hours
• Infants (<1 year): 62.5-125 mg every 6 hours

Common Side Effects:

• Skin rashes (urticaria, morbilliform or scarlatiniform rashes)
• Pruritus
• Eosinophilia
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Gastrointestinal disturbances
• Pseudomembranous colitis
• Anaphylactic reactions
• Angioneurotic edema
• Laryngeal edema
• Bronchial spasm
• Shock
• Leukopenia, granulocytopenia, agranulocytosis
• Hemolytic anemia
• Thrombocytopenia
• Pancytopenia
• Myelosuppression
• Drug-induced aseptic meningitis
• Encephalopathy (in overdose or renal impairment)

• Consider cross-allergy with cephalosporins
• Do not use in patients with severe GI disorders (with vomiting and diarrhea)
• Prolonged use may lead to proliferation of resistant organisms
• Consider sugar content in syrup for diabetic patients
• Risk of encephalopathy (in overdose or renal impairment)