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At a glance

Aspartame is a low-calorie artificial sweetener used as a sugar substitute. It is approximately 200 times sweeter than sucrose and is used in a variety of foods and beverages.

Indications
  • Diet supplement and sugar substitute
  • Low-calorie food and beverage sweetening
Pharmacology

Aspartame is a dipeptide compound (L-alpha-aspartyl-L-phenylalanine methyl ester) composed of two amino acids (aspartic acid and phenylalanine) and methanol.

Aspartame is approximately 200 times sweeter than sucrose. Upon digestion, it is completely hydrolyzed into aspartic acid, phenylalanine, and methanol, which are absorbed into the blood and used in normal metabolic processes.

Neither aspartame nor its components accumulate in the body.

Dosage

Use according to individual taste. 1 pellet is equivalent in sweetness to 1 teaspoon of sugar (approx. 2 calories).

Side effects
  • Constipation
  • Abdominal discomfort or pain
  • Heartburn
  • Flatulence
  • Nausea
  • Vomiting
  • Diarrhea
  • Skin rashes
  • Pruritus of the tongue, skin and perianal region

High doses: Steatorrhoea, hyperchloremic acidosis

Use in pregnancy

[CONSULT YOUR DOCTOR] Pregnancy Category C. Animal studies have shown adverse effects on the fetus. Pregnant women should use with caution.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Serious Precautions:

  • Phenylketonuria (PKU): Aspartame contains phenylalanine, which is harmful for PKU patients
  • Pregnancy and lactation: Use with caution
  • Patients taking certain medications: MAO inhibitors, sedatives, levodopa-containing drugs
  • Avoid long-term excessive use (may alter gut microbiome)
Overdose effects

Overdose may cause the side effects listed above. Consult a doctor if symptoms occur.

Storage conditions

Store below 30°C, in a cool and dry place, away from light. Keep out of reach of children.

Aspartame — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.