৳ 30.09/unit
Pack: ৳ 30.09
৳ 30.09/unit
Pack: ৳ 30.09
At a glance
Permethrin 5% Topical is an antiparasitic medication used for the treatment of scabies and crab lice infestations (Pediculosis). It causes paralysis and death of the pests by inhibiting sodium ion influx through nerve cell membrane channels.
Indications
- Scabies
- Pediculosis (crab lice infestations)
Pharmacology
Permethrin is a pyrethroid that disrupts sodium channel current on the nerve cell membrane, causing delayed repolarization and paralysis of the parasite. It is minimally absorbed through the skin (<0.5% over 48 hours) and rapidly metabolized in the liver, excreted primarily in urine.
Dosage
Adult Dose (Topical):
- Scabies (30 gm tube): Full tube; apply to skin surfaces from neck to toes; wash off after 8-14 hours; may reapply in 7 days
- Pediculosis: Apply to washed hair and leave on for 10 minutes before rinsing with water; may reapply in 7 days
Pediatric Dose (Topical):
- >12 years: Full tube
- 6-12 years: Up to ½ tube
- 1-5 years: Up to ¼ tube
- 2 months-1 year: Up to ⅛ tube
- Less than 2 months: Dose not established
Side effects
Common Side Effects:
- Skin burning
- Stinging or tingling sensation
- Erythema
- Edema
- Eczema
- Rash
- Pruritus
Use in pregnancy
Use in Pregnancy: Generally considered safe during pregnancy; animal studies have shown low or no adverse effects; limited human studies available.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Scabies infestation is often accompanied by pruritus, edema, and erythema; treatment may temporarily exacerbate these conditions
- Avoid contact with eyes; if the cream gets in the eyes, flush with water immediately
- If the condition persists after 14 days of treatment, the doctor may suggest another treatment
- Use in pregnancy only under medical advice
Overdose effects
No overdose information available; consult your doctor if overused.
Storage conditions
Store in a cool, dry place, away from light; keep out of reach of children.