Phensilex5mg/5ml
OTC- Generic:
- Promethazine Hydrochloride
- Company:
- Aztec Pharmaceuticals Ltd.
- Dosage form:
- Syrup
- Pack size:
- 60ml bot
৳ 10/unit
Pack: ৳ 10
At a glance
Promethazine Hydrochloride — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Promethazine Hydrochloride used in the treatment of various allergic conditions like runny nose, sneezing, congestion, itching and watery eyes. It also treats nausea, vomiting and insomnia (difficulty in sleeping) in adults and used as a sedative (sleep causing) in children (for 5 years and above). Promethazine Hydrochloride should be taken with or without food, but take it at the same time every day to get the most benefit. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. In case, you have missed any doses than it is better to take the next dose as soon as you remember it. However, you should never take a double dose. you must inform your doctor if symptoms does not get improve within 7 days of treatment. The most common side effects of this medicine include dry mouth, blur vision, headache, and feeling dizzy. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes skin more sensitive towards sunlight. use sunscreen or wear protective clothing before going out. Before taking this medicine, let your doctor know if you have glaucoma or have asthma issues or have high blood pressure. Inform your doctor if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment. Promethazine Hydrochloride is an antiallergic medication. When your body is exposed to an allergen (pollen, animal dander, house dust etc.), it produces a chemical called histamine. This causes watery eyes, runny or blocked nose, sneezing, skin rashes, itching etc. Promethazine Hydrochloride works by blocking the action of histamine, thereby relieving these symptoms. It also works directly on several areas of the brain to prevent nausea/vomiting and help you feel more relaxed.
Indications
• Nausea • Vomiting
Mechanism of action
Promethazine, a phenothiazine derivative, blocks postsynaptic dopaminergic receptors in the brain and has a strong alpha-adrenergic blocking effect. It competitively binds to H1-receptors.
Dosage
Adult Dose: Oral Allergic conditions Adult: As promethazine HCl: 25 mg at night, increase to 25 mg bid if necessary. Alternatively, 10-20 mg 2-3 times daily. Prophylaxis of motion sickness Adult: As promethazine HCl: 20 mg or 25 mg the night before travelling, followed by a similar dose the following morning if necessary. As promethazine teoclate: 25 mg given on the night or 1-2 hr before travelling. Short-term management of insomnia Adult: As promethazine HCl: 20-50 mg at night. Parenteral Allergic conditions; Sedation Adult: As promethazine HCl: 25-50 mg, by deep IM, IV inj or IV infusion at a rate of not more than 25 mg/min. Max: 100 mg. Nausea and vomiting Adult: As promethazine HCl: 12.5-25 mg, repeated at intervals of not less than 4 hr. Max: 100 mg daily. Child Dose: Oral Allergic conditions Child: As promethazine HCl: 2-5 yr 5-15 mg daily in 1 or 2 divided doses; >5-10 yr 10-25 mg daily in 1 or 2 divided doses. Prophylaxis of motion sickness Child: As promethazine HCl: 2-5 yr 5 mg; >5-10 yr 10 mg. Doses are given the night before the journey and repeated on the following morning (6-8 hr later) if necessary. Short-term management of insomnia Child: As promethazine HCl: 2-5 yr 15-20 mg; >5-10 yr 20-25 mg. Parenteral Allergic conditions; Sedation Child: As promethazine HCl: 5-10 yr 6.25-12.5 mg by deep IM. Renal Dose: Renal impairment: Dose reduction may be required.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Promethazine Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Promethazine Hydrochloride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Dryness in mouth • Blurred vision • Headache • Dizziness
Precautions & warnings
[UNSAFE] Promethazine Hydrochloride may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Promethazine Hydrochloride helps treat nausea and vomiting. It may also be used for the short-term treatment of sleeping difficulties (insomnia) in adults and as a sedative in children. Use caution while driving or doing anything that requires concentration as Promethazine Hydrochloride can cause dizziness and sleepiness. Do not drink alcohol while taking this medication as it may cause increased sleepiness. It may make your skin more sensitive to sunlight. Avoid exposing your skin to strong sunlight, use a sunscreen lotion or make sure your skin is protected with clothing. Do not take it for longer than 7 days. If your symptoms worsen or do not improve after 7 days, talk to your doctor. Stop taking it at least three days before taking an allergy test as it can affect the test results.
Contraindications
Patients in coma or suffering from CNS depression of any cause. Childn <2 yr. SC and intra-arterial admin. Concurrent use w/ or w/in 14 days of MAOI use.
Drug interactions
Masks ototoxicity of aminoglycoside antibiotics. May enhance the sedative effects of CNS depressants like alcohol, hypnotics, barbiturates and opioids. Potentially Fatal: Ventricular arrhythmias when used with drugs that prolong QT interval. Increased risk of extrapyramydal effects w/ MAOIs.
Food interactions
[UNSAFE] Promethazine Hydrochloride may cause excessive drowsiness with alcohol.
Use in pregnancy
[CONSULT YOUR DOCTOR] Promethazine Hydrochloride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Promethazine Hydrochloride is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. For prolonged use and repeated doses of Promethazine Hydrochloride, observe the baby for excessive sleepiness.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Promethazine Hydrochloride is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Promethazine Hydrochloride may not be needed in these patients. Please consult your doctor. However, caution is advised in patients with severe kidney disease as it may cause excessive sleepiness in them. [CAUTION] Promethazine Hydrochloride should be used with caution in patients with liver disease. Dose adjustment of Promethazine Hydrochloride may be needed. Please consult your doctor.
Common questions
Gastric nausea vomiting reflux sompraz D 40 mg twice daily 1 hour before meal for 10 days I am in the first month of pregnancy and I am experiencing nausea, vomiting, stomach pain (moderate to severe) as well as discomfort. Current medications is Susten SR 200 (OD), Duvadilan retard (OD), Doxinate (BD), Folverine D (OD), Fertigyn 500 (1 amp weekly) and aciloc 150 (BD). What should I do to ease my situation. Please suggest The med suggested are to support of pregnancy and for acidity and nausea and vomiting. Continue the same. You can upgrade the med for vomiting after consulting your My wife is 13 week pregnent her docter change her tablet from mvista to doxynate plus me I know the reason is both tablet aee same. Docter asked to taje doxynate plus 2 tablet at bed time.please suggest. Doxynate is tablet to stop vomiting dear. It is ok to take them at bed time. It is widely recommended to take for nausea and vomiting of pregnancy. Persistent hiccups. Doesn't stop for hours (sometimes for days). Cause pain in chest and vomiting. Sompraz d 1 st tablet in empty stomach I am 72 days pregnant. I can't able to eat anything. Always feeling vomiting. I am more worried about my baby. Will my baby get sufficient nutrition? Please start taking Doxinate tablet thrice a day to prevent nausea. As nausea decreases, you should be able to eat properly. Ravi site d tablet for back pain ?? How many days suffered back ache What is side effect of primolut n Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut. list the method of intake of the following tablet Lyser-D, scrip in, Omez-D, (for my wife) Hello PATIENT take these medicine as over the counter. Hopefully the doctor who has prescribed these medicine must wrote depend upon your need n requirement with there possible experience and knowledge