osudhkosh
New
Company•Navana Pharmaceuticals Ltd.

Pravalip 20

Rx
Generic: Pravastatin Sodium

৳ 15/unit

Pack: ৳ 150

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At a glance

Pravastatin Sodium is an HMG-CoA reductase inhibitor (statin) used as adjunctive therapy to diet to reduce the risk of MI, revascularization, and cardiovascular mortality in hypercholesterolemic patients, and to reduce elevated LDL-C, ApoB, and TG levels and increase HDL-C in patients with primary hypercholesterolemia and mixed dyslipidemia.

Indications
  • Reduce risk of MI, revascularization, and cardiovascular mortality in hypercholesterolemic patients without clinically evident CHD
  • Reduce coronary death, MI, revascularization, stroke/TIA, and progression of coronary atherosclerosis in patients with clinically evident CHD
  • Primary hypercholesterolemia and mixed dyslipidemia
  • Hypertriglyceridemia
  • Primary dysbetalipoproteinemia (not responding to diet)
  • Heterozygous familial hypercholesterolemia in children and adolescents ages 8 years and older
Pharmacology

Pravastatin is a specific inhibitor of hepatic HMG-CoA reductase. Inhibition of this enzyme reduces cholesterol biosynthesis, increasing the number of LDL receptors on cell surfaces and enhancing receptor-mediated metabolism and clearance of LDL. It also inhibits VLDL synthesis.

Dosage

Adult Dose (Oral):

  • Starting dose: 40 mg once daily
  • May increase to 80 mg/day if needed
  • Severe renal impairment: 10 mg/day

Pediatric Dose (8-13 years):

  • 20 mg once daily

Adolescent Dose (14-18 years):

  • Starting dose: 40 mg once daily
Side effects

Common Side Effects (≥2%):

  • Musculoskeletal pain
  • Nausea/vomiting
  • Upper respiratory infection
  • Diarrhea
  • Headache
Use in pregnancy

Use in Pregnancy: Pregnancy Category X; safety not established in pregnant women; use only if potential benefit outweighs potential risk to fetus.

Pregnancy Category: X — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Skeletal muscle effects (myopathy, rhabdomyolysis): Risk increases with advanced age (>65), uncontrolled hypothyroidism, renal impairment
  • Liver enzyme abnormalities; check before initiating therapy and as clinically indicated
Overdose effects

No overdose information available; consult your doctor if taken in excess.

Storage conditions

Store below 30°C, away from light and moisture; keep out of reach of children.

Pravastatin Sodium — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.