PregneedCapsule

Pregneed Capsule is a capsule manufactured by Chemist Laboratories Ltd. in Bangladesh. Its active ingredient is Iron + Folic acid + Vitamin B complex + Vitamin C.

Indications

This is indicated for the treatment and prophylaxis of Zinc, Iron, Folic Acid, Vitamin B Complex and Vitamin-C deficiency especially during pregnancy and lactation.

Contraindications

This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.

Composition

• Each capsule contains
• Zinc Sulphate Monohydrate 61.8 mg
• Dried Ferrous Sulphate 150 mg
• Folic Acid (Vitamin-B9) 0.50 mg
• Thiamine Mononitrate (Vitamin-B1) 2 mg
• Riboflavin (Vitamin-B2) 2 mg
• Nicotinamide (Vitamin-B3) 10 mg
• Pyridoxine Hydrochloride (Vitamin-B6) 1 mg
• Ascorbic Acid (Vitamin-C) 50 mg

Pharmacology

Zinc sulfate

precipitates protein and this is responsible for the astringent and weak antiseptic activity of Zn sulfate. It also produces mild vasodilation. Zinc sulfate can also be used orally or systemically as a zinc supplement. 220 mg of zinc sulfate (heptahydrate) contains 50 mg of elemental zinc.

Iron

is an essential mineral, with several important roles in the body. For example, it helps to make red blood cells, which carry oxygen around the body. A lack of iron can lead to iron deficiency anaemia. Liver is a good source of iron, don't eat it if you are pregnant. This is because it is also rich in vitamin A which, in large amounts, can harm your unborn baby.

Folic acid

is essential for the production of certain coenzymes in many metabolic systems such as purine and pyrimidine synthesis. It is also essential in the synthesis and maintenance of nucleoprotein in erythropoesis. It also promotes WBC and platelet production in folate-deficiency anaemia.

Nicotinamide

is a vitamin B3 derivative. It is incorporated into coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), which are involved in multiple cellular metabolic pathways.

Vitamin C

is necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid.

Vitamin B complex

: The building blocks for good health come from a variety of foods, even if they are from the same family of nutrients. Such is the case with vitamin B, a key player in maintaining cell health and keeping you energized.

Not all types of vitamin B do the same thing. Additionally, the different types of vitamin B all come from different types of foods.

Vitamin B deficiencies can lead to health problems. Sometimes a doctor will prescribe a supplement when they think you’re not getting enough.

Dosage & Administration

One capsule daily. In more severe cases, 2 capsules a day may be required or as directed by the physician.

Side Effects

Generally well tolerated. However, a few allergic reactions may be seen.

Precautions & Warnings

Care should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anaemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.

Overdose Effects

• Accidental overdose of iron containing products
• is a leading cause of fatal poisoning in children below 6 years. Avoid higher doses if you have liver disease or haemochromatosis; excess can cause bloody diarrhea, vomiting, acidosis, darkened stools, abdominal pain. Symptoms may clear in a few hours.
• Riboflavin
• is reported to be completely safe and no toxic symptoms have been reported so far. Higher doses of Nicotinamide may cause vomiting, diarrhea. Sensory neuropathy was observed in individuals consuming more than 200 mg Pyridoxine for very long periods. No case of Folic acid overdodage has been reported.
• Acute ingestion of Ascorbic acid
• , even of massive doses, is unlikely to cause significant effects.
• Zinc
• toxicity has been seen in both acute and chronic forms. Ingestion of 150 to 450 mg of zinc per day have been associated with low copper status, altered iron function, reduced immune function, and reduced levels of high-density lipoproteins. So, Zinc at its RDA dosages dose not cause any significant effect.

Therapeutic Class

Iron & Vitamin Combined preparations

Storage Conditions

Store in a dry place below 25 °C. Protect from light.

Disclaimer: This information is for reference only. Always consult a registered physician before taking any medicine.