৳ 70/unit
Pack: ৳ 1,960
৳ 70/unit
Pack: ৳ 1,960
At a glance
Estrogens is a female sex hormone (estrogen) used as hormone replacement therapy for menopause symptoms and osteoporosis prevention.
Indications
- Hormone Replacement Therapy: Used for menopause symptoms such as hot flushes, night sweats and vaginal dryness.
- Osteoporosis Prevention: Used for prevention of bone loss and fractures in postmenopausal women.
- Prostate Cancer: Used for palliative treatment.
- Breast Cancer: Used for palliative treatment in selected metastatic patients.
Pharmacology
Estrogens modulate pituitary secretion of gonadotropins, luteinising hormones and follicle-stimulating hormones through negative feedback mechanism, thus reducing elevated levels of hormones in postmenopausal women during oestrogen replacement therapy.
Dosage
Adult Dose (Oral):
- Menopausal Vasomotor Symptoms, Atrophic Vaginitis: 0.3 mg PO once daily (continuous or cyclic regimen)
- Female Hypogonadism: 0.3-0.625 mg PO once daily (cyclic: 3 weeks on, 1 week off)
- Osteoporosis Prophylaxis: 0.3 mg PO once daily (cyclic: 25 days on, 5 days off)
- Prostate Cancer (Palliative): 1.25-2.5 mg PO q8hr
- Abnormal Uterine Bleeding: 10-20 mg/day PO divided q4hr
- Breast Cancer (Palliative): 10 mg PO q8hr for >=3 months
Side effects
Common Side Effects:
- Bloating
- Breast pain
- Hair loss
- Headache
- Irregular vaginal bleeding
- Nausea
- Stomach cramp
- Vomiting
Use in pregnancy
Use in Pregnancy: Estrogens is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby.
Pregnancy Category: B3 — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- It is not known whether Estrogens alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
- Prescribed as part of HRT to relieve symptoms of menopause.
- Take at the same time every day.
- Inform your doctor if you experience any unusual vaginal bleeding, discharge or vaginal discomfort.
- May increase risk of breast cancer; have regular breast examinations.
- Stop taking and inform doctor immediately if unexplained swelling and pain in limbs, shortness of breath, chest pain, or changes in vision occur.
Overdose effects
Overdose: Limited information is available on overdose. Overdose may cause nausea, vomiting and withdrawal bleeding.
Storage conditions
Storage: Store below 30 degree C in a cool and dry place, away from light. Keep out of reach of children.