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At a glance

Metronidazole + Neomycin Sulphate + Nystatin + Polymyxin B Vaginal suppository is used for vaginal trichomoniasis leucorrhoea and mixed vaginal infections.

Indications
  • Vaginal trichomoniasis
  • Vaginal leucorrhoea
  • Bacterial or fungal vaginal infection
  • Mixed vaginal infections
Pharmacology

Metronidazole interacts with DNA causing destruction of helical structure. Nystatin binds to ergosterol affecting cell wall permeability. Polymyxin B disrupts bacterial cytoplasmic membrane. Neomycin binds to 30S ribosomal subunits inhibiting protein synthesis.

Dosage

Adult Dose (Vaginal Suppository):

  • Insert 1 suppository into the vagina at bedtime
  • Use for 12 days
Side effects

Side Effects:

  • Skin rash and urticaria (rare)
  • Local irritation (rare)
Use in pregnancy

Use in Pregnancy: Caution advised. Animal studies show adverse effects on fetus.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in renal impairment
  • Discontinue if sensitization occurs
  • For external use only
Overdose effects

No overdose information available (topical preparation).

Storage conditions

Store in a cool and dry place away from light. Keep out of reach of children.

Metronidazole + Neomycin Sulphate + Nystatin + Polymyxin B Vag — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.