৳ 3.01/unit
Pack: ৳ 30.10
৳ 3.01/unit
Pack: ৳ 30.10
At a glance
Fluoxetine is an SSRI antidepressant used for the treatment of depression, panic disorder, obsessive-compulsive disorder, and bulimia nervosa.
Indications
- Depression: Used for treatment of depressive illness.
- Bulimia Nervosa: Used to reduce binge-eating and purging.
- Obsessive-Compulsive Disorder: Used for treatment of OCD.
- Panic Disorder: Used for treatment of panic disorder.
Pharmacology
Fluoxetine has been shown to selectively inhibit the reuptake of serotonin at the presynaptic neuronal membrane which causes increased synaptic concentration of serotonin in the CNS. This results in numerous functional changes associated with enhanced serotonergic neurotransmission. Fluoxetine appears to have no effect on the reuptake of norepinephrine and dopamine and does not exhibit anticholinergic, antihistaminic or α1 adrenergic blocking activity at usual therapeutic doses.
Dosage
Adult Dose (Oral):
- Depression: Initial: 20 mg once daily; may increase up to 80 mg daily in 2 divided doses.
- Bulimia Nervosa: 60 mg daily as a single or in divided doses.
- OCD: Initial: 20 mg once daily; may increase up to 60 mg daily; Max: 80 mg daily.
- Panic Disorder: Initial: 10 mg once daily; increase to 20 mg daily after 1 week; may increase up to 60 mg daily.
- PMDD: 20 mg daily continuously or started 14 days before menstruation.
- Elderly: Max: 60 mg daily.
Child Dose (>7 years, OCD): Initial: 10 mg daily; may increase to 20 mg daily after 2 weeks; up to 60 mg daily if required.
Side effects
Common Side Effects:
- Erectile dysfunction
- Indigestion
- Influenza like syndrome
- Loss of appetite
- Low sexual desire
- Nausea
- Sore throat
- Sweating
- Tremor
- Weakness
- Yawning
- Abnormal dreams
- Delayed ejaculation
- Dry mouth
- Insomnia
- Nervousness
- Sleepiness
- Sinus infection
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies have shown harmful effects; doctor will weigh benefits and potential risks.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Fluoxetine may affect your ability to drive.
- Take in the morning (can keep you awake if taken late at night).
- May cause anxiety and agitation when first starting.
- May cause weight loss and decreased appetite.
- Talk to doctor if sudden mood changes or suicidal thoughts occur.
- Inform doctor if difficulty having orgasm or decreased sex drive.
- Addiction/dependence potential is very less.
- Do not stop taking suddenly without doctor consultation.
Overdose effects
Overdose: Overdose may cause nausea, vomiting, drowsiness, dizziness, seizures, serotonin syndrome; symptomatic treatment.
Storage conditions
Storage: Keep below 30 degree C, away from light and moisture. Keep out of reach of children.