osudhkosh
New
Company•Rainbow Traders

Rasilez

300mgRx
Generic: Aliskiren

৳ 1/unit

Pack: ৳ 1

TabletTablet
Save to my medicines
Alert me on price drop

At a glance

Aliskiren is a direct renin inhibitor used for the treatment of hypertension (high blood pressure). It relaxes blood vessels, lowers blood pressure, and reduces the risk of heart attack and stroke.

Indications

Hypertension (high blood pressure).

Pharmacology

Aliskiren directly inhibits the enzyme renin at the first step of the renin-angiotensin system (RAS). It prevents the conversion of angiotensinogen to angiotensin I, resulting in decreased levels of angiotensin II and aldosterone. This leads to vasodilation, reduced peripheral vascular resistance, and decreased blood pressure. Unlike other RAS inhibitors, aliskiren decreases rather than increases plasma renin activity.

Dosage

Adults: 150-300 mg once daily, with or without food (but consistently).

Maximum dose: 300 mg once daily.

Special populations:

  • Caution in severe heart failure, sodium or volume depletion
  • Discontinue if severe and persistent diarrhea occurs
  • Discontinue as soon as possible when pregnancy is detected
Side effects

Common side effects:

  • Diarrhea
  • Dizziness
  • Joint pain
  • Increased blood potassium levels
Use in pregnancy

Pregnancy Category: D

Aliskiren is highly unsafe during pregnancy. It affects the renin-angiotensin system causing oligohydramnios, which may result in fetal injury and/or death. Discontinue as soon as pregnancy is detected.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Highly unsafe during pregnancy (may cause fetal injury or death)
  • Caution in severe heart failure, sodium/volume depletion
  • Discontinue if severe and persistent diarrhea occurs
  • Caution in patients with history of angioedema
  • Contraindicated in severe renal impairment
  • Avoid concomitant use with ACE inhibitors or ARBs in patients with diabetes and renal impairment
  • Caution while driving (may cause dizziness)
Overdose effects

Overdose symptoms: significant hypotension, dizziness, electrolyte imbalance. Treatment: symptomatic and supportive measures.

Storage conditions

Store below 30°C in a cool and dry place, protected from light. Keep out of reach of children.

Aliskiren — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.