Rematib15mg
OTC- Generic:
- Upadacitinib
- Company:
- Drug International Ltd.
- Dosage form:
- Tablet
- Pack size:
- Box (10 Tablet)
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৳ 250/unit
Pack: ৳ 2,500
Price comparison
- This brand
- ৳ 250
- Cheapest of this genericReucent XR 15
- ৳ 100
The cheaper brand costs ৳ 150.00 less per unit
Compared against 6 brands
At a glance
Upadacitinib is a Janus kinase (JAK) inhibitor indicated for moderate to severe active rheumatoid arthritis, psoriatic arthritis, atopic dermatitis, ulcerative colitis, Crohn's disease, ankylosing spondylitis, non-radiographic axial spondyloarthritis, and polyarticular juvenile idiopathic arthritis.
Indications
- Rheumatoid arthritis
- Psoriatic arthritis
- Atopic dermatitis
- Ulcerative colitis
- Crohn's disease
- Ankylosing spondylitis
- Non-radiographic axial spondyloarthritis
- Polyarticular juvenile idiopathic arthritis
Dosage
Adult Dose (Oral):
- Rheumatoid arthritis: 15 mg once daily
- Psoriatic arthritis: 15 mg once daily
- Atopic dermatitis (12 years and older, weighing at least 40 kg): 15 mg once daily; may increase to 30 mg once daily
- Ulcerative colitis: Induction 45 mg once daily for 8 weeks; maintenance 15 mg once daily
- Crohn's disease: Induction 45 mg once daily for 12 weeks; maintenance 15 mg once daily
- Ankylosing spondylitis: 15 mg once daily
- Non-radiographic axial spondyloarthritis: 15 mg once daily
- Polyarticular juvenile idiopathic arthritis (30 kg and greater): 15 mg once daily
Hepatic Impairment: Mild or moderate: no dose adjustment; Severe: not recommended
Side effects
Common Side Effects:
- Upper respiratory tract infection (13.5%)
- Nausea (3.5%)
- Neutropenia (1.1-2.4%)
- Lymphopenia (0.3-2.4%)
- Cough (2.2%)
- Elevated ALT (0.8-2.1%)
- Increased creatine phosphokinase (0.3-1.6%)
- Elevated AST (1-1.5%)
- Pyrexia (1.2%)
- Pneumonia, herpes zoster, herpes simplex, oral candidiasis, anemia (<0.1%)
Precautions & warnings
- Malignancies reported; consider risks and benefits before initiating in patients with known malignancy
- Thrombosis reported, including DVT, PE, and arterial thrombosis
- Gastrointestinal perforation reported
- May cause neutropenia, lymphopenia, anemia, elevated lipids, or elevated liver enzymes; monitor for abnormal laboratory values
- May cause fetal harm based on animal studies; do not use during pregnancy
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.