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At a glance

Risedronate Sodium + Calcium is a combination used for the treatment and prevention of osteoporosis in postmenopausal women, to increase bone mass in men with osteoporosis, and for Paget's disease of bone.

Indications
  • Treatment and prevention of osteoporosis in postmenopausal women
  • Increase bone mass in men with osteoporosis
  • Paget's disease of bone
Pharmacology

Risedronate inhibits bone resorption by inhibiting osteoclasts. Calcium prevents or treats negative calcium balance, facilitates nerve and muscle performance and normal cardiac function, and plays a key role in bone mineralization and enzymatic reactions.

Dosage

Adult Dose (Oral):

  • Once weekly: 1 risedronate tablet on Day 1, then 1 calcium 500 mg tablet daily with food on the remaining 6 days
Side effects

Side Effects:

  • Chest pain
  • Difficulty or pain when swallowing
  • Pain or burning under the ribs or in the back
  • New or worsening heartburn
  • Severe joint, bone, or muscle pain
  • Jaw pain, numbness, or swelling
  • Mild heartburn or stomach upset
  • Diarrhea, gas, constipation
  • Mild joint or back pain
  • Headache
Use in pregnancy

Use in Pregnancy: Do not use during pregnancy; if accidentally taken, stop immediately and consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Correct hypocalcemia before therapy
  • Ensure adequate calcium and vitamin D intake
  • Avoid in severe renal impairment (CrCl <30 mL/min)
  • Do not use in pregnancy and lactation
Overdose effects

Overdose: Decreases in serum calcium; signs and symptoms of hypocalcemia; treatment: milk or antacids containing magnesium, calcium, or aluminum; in substantial overdose, gastric lavage may be considered.

Storage conditions

Store in a cool and dry place, protected from light; keep out of reach of children.

Risedronate Sodium + Calcium — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.