RP20mg
Rx- Generic:
- Rabeprazole
- Company:
- Globe Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 6.90/unit
Pack: ৳ 69
At a glance
Rabeprazole — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Rabeprazole is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as heartburn, acid reflux, peptic ulcer disease, and some other stomach conditions associated with excessive acid production. Rabeprazole is also used to prevent stomach ulcers and acidity that may be seen with the prolonged use of pain-killers. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine should be taken one hour before a meal, preferably in the morning. The dose will depend on your underlying condition and how you respond to the medicine. Try to take it regularly at the same time each day as advised by your doctor. You should keep on taking it as prescribed even if your symptoms disappear quickly. You may be able to help improve your symptoms by eating smaller meals more often and avoiding caffeinated drinks like tea and coffee, and spicy or fatty foods. The most common side effects that may be seen with this medicine include nausea, vomiting headache, dizziness, flatulence, diarrhea, and stomach pain. These tend to be mild but talk to your doctor if they bother you or do not go away. The risk of side effects may increase the longer you take this medicine. Long-term use (more than 1 year) may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements. Low blood magnesium levels (hypomagnesemia) have been seen in some people taking this medicine for 3 months or more. This may lead to tiredness, confusion, dizziness, muscle twitches, and an irregular heartbeat. Your doctor may monitor your magnesium levels to prevent this. Rabeprazole is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy. Rabeprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
Indications
• Gastroesophageal reflux disease (Acid reflux) • Peptic ulcer disease
Mechanism of action
Rabeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase at the secretory surface of the gastric parietal cell.
Dosage
Adult Dose: Oral Gastro-oesophageal reflux disease Adult: 20 mg daily for 4-8 wk. Maintenance: 10 or 20 mg/day. All doses to be taken once in the morning. Zollinger-Ellison syndrome Adult: Initially, 60 mg once in the morning, adjusted to max dose of 120 mg/day if needed. Daily doses >100 mg should be given in 2 divided doses. Peptic ulcer Adult: 20 mg once in the morning for 4-8 wk (duodenal ulcer) or for 6-12 wk (gastric ulcer). H.pylori infection Adult: 1-wk triple therapy: 20 mg bid combined w/ clarithromycin 500 mg bid and amoxicillin 1 g bid or combined w/ clarithromycin 250 mg bid and metronidazole 400 mg bid. Erosive oesophagitis Adult: 20 mg/day for 4-8 wk. May continue for another 8 wk if healing is incomplete. Maintenance: 10 or 20 mg/day. All doses to be taken once in the morning. Elderly: No dosage adjustment needed. Hepatic impairment: No dosage adjustment needed. Child Dose: Delayed-release capsule (sprinkles) 15 kg): 10 mg PO qDay 30 minutes before a meal, for up to 12 weeks Gastroesophageal Reflux Disease Delayed-release tablet 12 years: 20 mg PO qDay for up to 8 weeks Renal Dose: Renal impairment: No dosage adjustment needed.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rabeprazole is to be taken empty stomach.
Missed dose
If you miss a dose of Rabeprazole, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Diarrhea • Dizziness • Flatulence • Headache • Nausea • Sore throat • Stomach pain • Vomiting
Precautions & warnings
[CONSULT YOUR DOCTOR] It is not known whether Rabeprazole alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. It is a well-tolerated medicine and provides relief for a long time. Avoid eating late at night or before bedtime. Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away. Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention. Long-term use of Rabeprazole can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor. Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Contraindications
Rabeprazole is contraindicated in patients with known hypersensitivity to Rabeprazole, other PPIs or to any component of the formulation.
Drug interactions
May decrease serum concentration of ketoconazole, itraconazole and clopidogrel. Increased risk of hypomagnesaemia w/ diuretics and digoxin. May increase prothrombin time and INR of warfarin. May increase plasma concentration of saquinavir and methotrexate. Decreased serum levels w/ sucralfate. Potentially Fatal: May decrease plasma concentrations and pharmacological effects of rilpivirine and atazanavir.
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Rabeprazole. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Rabeprazole may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Rabeprazole is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Rabeprazole is safe to use in patients with kidney disease. No dose adjustment of Rabeprazole is recommended. [CAUTION] Rabeprazole should be used with caution in patients with severe liver disease. Dose adjustment of Rabeprazole may be needed. Please consult your doctor.
Common questions
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed Having problem of acid reflux disease with throat infection and pain in right side of abdomen take avipattikar churan 1 spoon twice before meal, for throat infection do gargles with lyuke warm water and mixing tankan bhasma a littlein it,, My cough is not getting cured since 4-6 months. Tried some doctors, their medicines work for some time and the dry cough starts again. Though it happens occasionally, but i still cough It can be allergic cough or acid reflux disease. Can't give more opinion without seeing acid reflux, gastric, sugar stimulate acid reflux. CBC,ESR,LIPID PROFILE,URINE RE/CS, KFT, LFT, VIT D & B estimation,TAKE RABEKIND DSR once a day empty stomach FOR 3 week Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly, Moderate Throat Pain in left side Moderate Ear pain. Acid reflux too often it may be due to acidity also you may have got some ulcer or infection in that region visit ent specialist near you for proper examination I take razo 20 but not relif what I do Good physical activity Avoid stress Less Tea, coffee and milk More curd and butter milk Should meet a gastroenterologist Grade one fatty liver with excessive bowel gases seen? Acid peptic disease /colities. Ok tell me the duration of problem