Sandostatin Lar20mg(largedose)

Octreotide is used in the treatment of acromegaly, carcinoid tumors, and bleeding esophageal varices. It is also used to prevent complications following surgery of the pancreas. Octreotide is generally given by a healthcare professional. You should not self-administer this medicine at home. Your doctor will decide the dose and how often you should take them. You should use it regularly to get the most benefit from the medicine. Do not stop using the medicine even if you feel better unless the doctor tells you so. Using this medicine may cause few common side effects such as diarrhea, abdominal pain, nausea, constipation, flatulence, and headache. Let your doctor know if any of these side effects do not go away or get worse. Before using this medicine, inform your doctor if you have problems with your liver. You should also tell your doctor all the other medicines you are taking. Octreotide is a similar to somatostatin, a substance normally found in the human body which inhibits the effects of certain hormones such as growth hormone. It also lowers the bleeding from the food pipe by constricting (narrowing) the blood vessels.

• Acromegaly • Carcinoid tumours • Bleeding esophageal varices

Octreotide is a synthetic analogue of somatostatin which acts by suppressing basal and stimulated secretion of growth hormone (GH). It also suppresses LH response to gonadotrophin-releasing hormone and reduces the secretion of gastrin, vasoactive intestinal peptide (VIP), insulin, glucagon, secretin, motilin and pancreatic polypeptide.

Adult Dose: Acromegaly Solution: 50 mcg SC q8hr initially; titrate up to 500 mcg SC q8hr if necessary; after successful treatment with solution for 2 weeks, initiate treatment with suspension (depot injection) Suspension (depot injection): 20 mg IM (gluteal) every 4 weeks for 3 months; titrate up or down to 10-30 mg IM every 4 weeks, depending on response; not to exceed 40 mg, as follows Symptoms controlled: If GH 2.5 ng/mL or IGF-I elevated, increase dose to 30 mg IM every 4 weeks; if symptoms persist, increase to 40 mg IM Carcinoid Tumor Solution: 100-600 mcg/day SC divided q6-12hr; may titrate to 1500 mcg/day; after successful treatment with solution for 2 weeks, initiate treatment with suspension (depot injection) Suspension (depot injection): 20 mg IM every 4 weeks if regular injection well tolerated Subcutaneous Prophylaxis of complications following pancreatic surgery Adult: 100 mcg tid of a rapid-acting preparation given for 7 consecutive days, starting at least 1 hr before operation. HIV-associated diarrhoea Adult: Initial dose 100 mcg tid. If symptoms are not controlled after 1 wk, increase dose to 500 mcg tid. Intravenous Variceal haemorrhage in patients with cirrhosis Adult: As continuous IV infusion: 25 mcg/hr for 48 hr (up to 5 days in patients at high risk of re-bleeding). Hepatic impairment: Cirrhosis, 10 mg IM every 4 weeks initially, then titrate to effect Child Dose: Safety and efficacy not established Renal Dose: Renal impairment: Without dialysis, dose adjustment not necessary; with dialysis, 10 mg IM every 4 weeks initially, then titrate to effect

Your doctor or nurse will give you this medicine. Kindly do not self administer.

If you miss a dose of Octreotide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Diarrhea • Abdominal pain • Nausea • Constipation • Flatulence • Headache • Increased glucose level in blood • Injection site reaction

[SAFE] Octreotide does not usually affect your ability to drive. Octreotide helps treat acromegaly and certain hormone-producing tumors of stomach, liver, and pancreas. It is given as an injection under the skin or into a vein. It may temporarily cause pain at the site of injection. You can relieve this by gently rubbing the site of injection for a few seconds afterwards. When used long term, your doctor may monitor your thyroid function, gallbladder function, liver function and vitamin b12 levels regularly. Inform your doctor if you are taking medicines to control your blood pressure or if you are diabetic. Women who do not wish to conceive should practice an effective method for contraception while taking this medication.

Hypersensitivity.

Dosage adjustment of concurrent therapy may be necessary with calcium channel blockers, oral hypoglycaemics, ?-blockers, diuretics. May increase concentration of bromocriptine. Potentially Fatal: Requirements of insulin may be reduced requiring careful blood-glucose monitoring. Reduction in ciclosporin bioavailability and efficacy.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Octreotide. Please consult your doctor.

[SAFE IF PRESCRIBED] Octreotide is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[SAFE IF PRESCRIBED] Octreotide is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[SAFE IF PRESCRIBED] Octreotide is safe to use in patients with kidney disease. No dose adjustment of Octreotide is recommended. [CAUTION] Octreotide should be used with caution in patients with liver disease. Dose adjustment of Octreotide may be needed. Please consult your doctor.

My doctor ask me to take vit k injection. I am 35 week pregnant. Why this injection is necessary? Your blood must be showing some abnormal results regarding clotting. This injections are given to prevent excessive bleeding during delivery I have one child.is there is any injection for prevent the pregnancy. Yes inj are there but they need to be taken every 3 months. They can cause irregular bleeding or spotting or slight weight gain. I am having ulcers in my mouth due to which i cant eat food secondly whenever i eat i feel burning in my chest . suffering from such condition since a month my doctor told me that i m deficit of vitamin . but he didnt say which vitamin . so i want to know if he is right You have gastritis and Gastro esophageal reflux. Can take sompraz-IT OD before breakfast n syp digene thrice daily 2tsf. My son got injured during cycling and bleeding occurred. Now bleeding stopped and he is feeling pain.The ruptured area is of size 4cm x 3cm approx.We have applied coconut oil. In the medical shop ,they have give two tablets Voltafram 50 and cefaclass 100.Can he take those tablets and what medication / precautions we have to take. Get TT injection if not already vaccinated and get Dressing done from a Doctor. Give Tab Dolo 500 1 tab SOS for pain Base of the breast like tumours formed 4 months back but at that time there is no pain.but now pain. Get it examined in the clinic I need some consultation related with contraceptive pills use. We need some gap for our next baby so use of pills is a better option or not? If yes, which injection or tablet you would like to suggest who have minimal side effects. Please confirm. Thanks! Yes tablets are goodDaily for 21 days starting from first day of bleeding What is the cause of enlarge spleen and liver? What treatment to be given? What precautions should be taken? Problem has got repeated in 2 months Please consult Dr. will take detail history and will examine your child in detail All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.There are many causes of liver and spleen enlargementfew examples--Infection: Acute viral hepatitis. Infectious mononucleosis. Haematological disease: Myeloproliferative disease. Leukaemia. Metabolic disease: Niemann-Pick disease. Chronic liver disease and portal hypertension: Chronic active hepatitis. Amyloidosis. Acromegaly. Systemic lupus erythematosus. Sarcoidosis. I have used preganews and i got positive result that means i am pregnant so plz give me any medicine name or injection i don't want pregnency hi PATIENT u r pregnant simply go to a govt hospital to a gynaecologist and get it aborted by simple method. there is no way u can do this at home and its illegal too and if more bleeding occurs u can die too so don't take risk. its very easy aajkal, just visit a govt hospital