osudhkosh
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Company•General Pharmaceuticals Ltd.

Sedron

5mgRx
Generic: Risedronate Sodium (Risedronic acid)

৳ 8.05/unit

Pack: ৳ 8.05

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At a glance

Risedronate Sodium is a bisphosphonate used for the treatment and prevention of osteoporosis in postmenopausal women, to increase bone mass in men with osteoporosis, and for the treatment of Paget's disease of bone.

Indications
  • Treatment and prevention of osteoporosis in postmenopausal women
  • Increase bone mass in men with osteoporosis
  • Prevention and treatment of corticosteroid-induced osteoporosis
  • Paget's disease of bone
Pharmacology

Risedronate has affinity for hydroxyapatite crystals in bone and acts as an antiresorptive agent. At the cellular level, it inhibits osteoclasts. Osteoclasts adhere normally to the bone surface but show evidence of reduced active resorption.

Dosage

Adult Dose (Oral):

  • Postmenopausal osteoporosis (treatment): 5 mg daily OR 35 mg once weekly OR 150 mg once monthly
  • Men with osteoporosis: 35 mg once weekly
  • Corticosteroid-induced osteoporosis: 5 mg daily
  • Paget's disease: 30 mg daily for 2 months; may repeat after 2-month interval if needed
Side effects

Side Effects:

  • Arthralgia
  • Back pain
  • GI disturbances (abdominal pain, dyspepsia)
  • Hypersensitivity reactions (angioedema, rash)
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Alopecia
  • Iritis, uveitis
  • Osteonecrosis of the jaw
  • Atypical femur fractures
Use in pregnancy

Use in Pregnancy: Do not use during pregnancy (intended only for postmenopausal women); if accidentally taken, stop immediately and consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Correct hypocalcemia before therapy
  • Ensure adequate calcium and vitamin D intake
  • Caution in esophageal abnormalities (stricture, achalasia)
  • Avoid in severe renal impairment (CrCl <30 mL/min)
  • Do not use in pregnancy and lactation
Overdose effects

Overdose: Decreases in serum calcium; signs and symptoms of hypocalcemia; treatment: milk or antacids containing magnesium, calcium, or aluminum; in substantial overdose, gastric lavage may be considered.

Storage conditions

Store in a cool and dry place, protected from light and moisture; keep out of reach of children.

Risedronate Sodium (Risedronic acid) — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.