oshudhkosh

Sefur125mg

Rx
Generic:
Cefuroxime
Dosage form:
Tablet
Pack size:
Strip (6 Tablet)

৳ 15.10/unit

Pack: ৳ 90.60

At a glance

Cefuroxime — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Cefuroxime is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (e.g. pneumonia), ear, throat, nasal sinus, urinary tract, skin, soft tissues, bones, and joints. It is also used to prevent infections during surgery. Cefuroxime is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. Your doctor will decide the correct dose for you. You should use this medicine regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The most common side effects of this medicine include rash, vomiting, diarrhea, increased liver enzymes and nausea. Some people may develop temporary redness or pain at the site of injection. These side effects are usually mild but let your doctor know if they bother you or last more than a few days. Before using it, you should tell your doctor if you are allergic to any antibiotics, and if you have any liver or kidney problems. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Cefuroxime is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Indications

• Bacterial infections

Mechanism of action

Cefuroxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Dosage

Adult Dose: Pharyngitis/Tonsillitis 250 mg PO q12hr for 10 days Acute Bacterial Maxillary Sinusitis 250 mg PO q12hr for 10 days Acute Bacterial Exacerbations of Chronic Bronchitis 250-500 mg PO q12hr for 10 days 500-750 mg IV q8hr; switch to oral therapy as soon as clinically possible Secondary Bacterial Infections of Acute Bronchitis 250-500 mg PO q12hr for 5-10 days Uncomplicated Pneumonia 750 mg IV/IM q8hr Uncomplicated Skin/Skin Structure Infections 250-500 mg PO q12hr for 10 days 750 mg IV/IM q8hr; switch to oral therapy as soon as clinically possible Uncomplicated Urinary Tract Infections 125-250 mg PO q12hr for 7-10 days 750 mg IV/IM q8hr; switch to oral therapy as soon as clinically possible Gonorrhea Uncomplicated: 1 g PO once or 1.5 g IM once at 2 different sites with 1 g probenecid PO Disseminated: 750 mg IV/IM q8hr Early Lyme Disease 500 mg PO q12hr for 20 days Severe or Complicated Infections 1.5 g IV/IM q8hr; may be administered q6hr in life-threatening situations Oral Susceptible infections Adult: 250 mg bid. Parenteral Susceptible infections Adult: 0.75 g 8 hrly, by deep IM or slow IV inj over 3-5 min or IV infusion, may increase up to 1.5 g 6-8 hrly in more severe infections. Child Dose: Children: PO 20–30 mg/kg/day q12h For bone and joint infections, up to 100 mg/kg/day IV, IM 100–150 mg/kg/day q8h Renal Dose: Renal impairment: Patients undergoing haemodialysis should receive an additional 750-mg dose after each dialysis; those undergoing continuous peritoneal dialysis may be given 750 mg bid. CrCl (ml/min) 10-20 750 mg bid. <10 750 mg once daily.

Administration

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Missed dose

If you miss a dose of Cefuroxime, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Common: • Rash • Vomiting • Allergic reaction • Increased liver enzymes • Nausea • Injection site reaction • Diarrhea

Precautions & warnings

[NOT RELEVANT] Not relevant, as Cefuroxime is intended for use in hospitalised patients. Your doctor has prescribed Cefuroxime to cure your infection and improve your symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat. Discontinue Cefuroxime and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools. Avoid consuming alcohol while taking Cefuroxime as it may cause increased side effects.

Contraindications

Hypersensitivity to cephalosporins.

Drug interactions

May enhance the nephrotoxic effect of strong-acting diuretics (e.g. furosemide) and aminoglycosides. May enhance the effect of oral anticoagulants. May reduce the efficacy of OCs. Probenecid prolongs the excretion of cefuroxime and elevated peak serum level.

Food interactions

[SAFE] Consuming alcohol with Cefuroxime does not cause any harmful side effects.

Use in pregnancy

[SAFE IF PRESCRIBED] Cefuroxime is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Use in lactation

[SAFE IF PRESCRIBED] Cefuroxime is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Avoid prolonged use of Cefuroxime, since it may have possible effects such as rash and diarrhea.

Renal / hepatic impairment

[CONSULT YOUR DOCTOR] There is limited information available on the use of Cefuroxime in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Cefuroxime in patients with liver disease. Please consult your doctor.

Common questions

CAN I TAKE CEFUROXIME IN CASE OF PREGNANCY Yes you can if needed I think I have bipolar disorder what medicine I could take Sorry wrong image send Divalproex sodium is a good medicine for bipolar disorder low blood pressure reasons and treatment plz told me coz i hv seen. sm friends suffering these deases mainly in early morning vertigo vomiting please shere your views Dear 1mg user, people who have low sodium they will have this problem go for blood test sodium and potassium and get treatment Zeptol 300 disadvantage plz ans. can cause fall in sodium levels rarely Sodium level of blood drops frequently Ok send me your all reports Sodium level of blood drops frequently send all the lab reports and your medical records My Wife taking occasionly Clindamycin +Cefuroxime & some times Spiromycin as antibiotics. And Antihistamines hot gargles as treatment Don&#x27;t use any medicine without consulting doctor

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.