Siglita 100

Sitagliptin is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness. Sitagliptin is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or along with other diabetes medicines. It may be taken on an empty stomach or with a meal. The dose will depend on your condition, and blood sugar levels. Therefore, you should use it as advised by your doctor. You should take it regularly at the same time each day to get the most benefit, and you should not stop unless your doctor recommends. This medicine is helping you to control your blood sugar levels and prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes. The most common side effect of taking this medicine is headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it. It may also cause upper respiratory tract infections like sore throat, cough and cold. Contact your doctor if the side effects worry you or if they do not go away. Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with this medicine's working. So, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly. Sitagliptin is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

• Type 2 diabetes mellitus

Sitagliptin inhibits dipeptidyl peptidase IV (DPP-IV), resulting in prolonged active incretin levels. Incretin hormones increases insulin synthesis and release from pancreatic beta-cells and reduces glucagon secretion from pancreatic beta-cells. Reduced glucagon secretion leads to decreased hepatic glucose production.

Adult Dose: Oral Type 2 diabetes mellitus Adult: 100 mg once daily. Hepatic impairment Mild to moderate impairment: Dose adjustment not necessary Severe impairment: Not studied Child Dose: Safety and efficacy not established Renal Dose: Renal impairment CrCl >50 mL/min: Dose adjustment not necessary CrCl 30-50 mL/min: 50 mg PO qDay CrCl <30 mL/min: 25 mg PO qDay ESRD: 25 mg PO qDay regardless of hemodialysis

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitagliptin may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Sitagliptin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Headache • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea • Upper respiratory tract infection • Nasopharyngitis (inflammation of the throat and nasal passages)

[CAUTION] Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur. Sitagliptin should be taken at the same time every day since this helps you remember to take it. It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety. Be careful while driving or operating machinery until you know how Sitagliptin affects you. Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

Hypersensitivity reactions such as anaphylaxis, angioedema, and exfoliative skin conditions including Stevens-Johnson syndrome can occur. Type 1 diabetes. Diabetic ketoacidosis.

Increased risk of hypoglycaemia when used in combination w/ sulfonylureas or insulin.

[UNSAFE] It is unsafe to consume alcohol with Sitagliptin.

[SAFE IF PRESCRIBED] Sitagliptin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[SAFE IF PRESCRIBED] Sitagliptin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Sitagliptin should be used with caution in patients with kidney disease. Dose adjustment of Sitagliptin may be needed. Please consult your doctor. [SAFE IF PRESCRIBED] Sitagliptin is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Sitagliptin may not be needed in these patients. Please consult your doctor.

Can i use tenali 20mg instead od januvia 100mg Before decide to change the medicine it is very important to know about your sugar level variations.So discuss with your doctor as he knows your all medical history Which medicine I can take instead of Januvia 100. It is very costly tablet. januvia is nowhere written in the prescription Alopathic medicine JANUVIA can be replaced by Right Suger Tablet right sugar tablet is not an allopathic medicine.so it can&#x27;t replace januvia Diabetes mellitus type 2 ,thirst A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET I am suffering from type 2 diabetes since last 3years and hypertension from 6years. I am taking medication morning januvia 100mg,glycomet 500sr a long H and at night glycomet 500sr ,rozavel10 Bp 120/80 normal and blood sugar with in 140, Good, keep it up Can you reply back geniune subsititue for Januvia 50 tablet. My father is using Januvia 50 tablet since last 1 year for diabities control. Working well but he is thinking for a cheaper substitute of Januvia 50 . If any good & safe substitute is available kindly reply bacl It is good medicine Diabetes mellitus type 2 required only ayurvedic medicine Go for allopathic medicine