Simplovir Oral Suspension200mg/5ml
Rx- Generic:
- Acyclovir
- Company:
- Incepta Pharmaceuticals Ltd.
- Dosage form:
- Suspension
- Pack size:
- 70ml bot
৳ 125/unit
Pack: ৳ 125
At a glance
Acyclovir — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Acyclovir is an antiviral medicine. It helps in treating viral infections like herpes labialis, herpes simplex virus infections, shingles, genital herpes infection, and chickenpox. It prevents the multiplication of virus in human cells and therefore helps in clearing the infection. Acyclovir should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Dissolve it in a glass of water before taking it. It may be taken with or without food, but it is better to take it at a fixed time. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage. Some side effects of this medicine include headache, dizziness, vomiting, nausea, fatigue, and fever. Inform your doctor if these side effects do not resolve or persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Acyclovir is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.
Indications
• Herpes simplex virus infections • Chickenpox • Herpes labialis • Shingles • Genital herpes infection
Mechanism of action
May be taken with or without food. May be taken w/ meals to reduce GI discomfort. Reconstitution: Add 10 mL or 20 mL of sterile water for inj to a vial labeled as containing 500 mg or 1,000 mg of aciclovir, respectively, to provide a soln containing 50 mg/mL. The appropriate dose of reconstituted soln should then be withdrawn from the vial and diluted w/ 50-125 mL of a compatible IV infusion soln.
Dosage
Adult Dose: Renal impairment. Pregnancy, lactation. Neurological abnormalities with significant hypoxia, serious hepatic or electrolyte abnormalities. Maintain adequate hydration. Lactation: Drug enters breast milk; use with caution. Renal Dose: Activity against HSV types I and II and varicella-zoster virus is due to intracellular conversion of aciclovir to the monophosphate by viral thymidine kinase with subsequent conversion to the diphosphate and active triphosphate by cellular enzymes. This active form inhibits viral DNA synthesis and replication by interfering with viral DNA polymerase enzyme and being incorporated into viral DNA.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Acyclovir may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Acyclovir, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Headache • Dizziness • Vomiting • Nausea • Fatigue • Fever • Stomach pain • Diarrhea • Skin rash • Photophobia
Precautions & warnings
[SAFE] Acyclovir does not usually affect your ability to drive. Do not skip any doses and finish the full course of treatment even if you feel better. Drink plenty of water while on treatment with this medicine. This helps to prevent dehydration and kidney damage. If you have genital herpes, use barrier methods (condoms) for contraception and avoid sexual contact while the sores are present. Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Contraindications
Child: PO 900 mg/m2/day q8h 60–80 mg/kg/day (max 4 g/day) q6–8h Varicella Zoster (Chickenpox) >2 years and 10 mL/min/1.73 m²: 200 mg q4hr (five times daily) 400 mg every 12 hr 0-10 mL/min/1.73 m²: 200 mg q12hr >10 mL/min/1.73 m²: 400 mg q12hr 800 mg every 4 hr 0-10 mL/min/1.73 m²: 800 mg q12hr 10-25 mL/min/1.73 m²: 800 mg q8hr >25 mL/min/1.73 m²: 800 mg q4hr (five times daily)
Drug interactions
Hypersensitivity.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Acyclovir. Please consult your doctor.
Use in pregnancy
[SAFE IF PRESCRIBED] Acyclovir is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Acyclovir is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Renal / hepatic impairment
[CAUTION] Acyclovir should be used with caution in patients with kidney disease. Dose adjustment of Acyclovir may be needed. Please consult your doctor. It is advisable to drink plenty of water while you are taking this medicine. [SAFE IF PRESCRIBED] Acyclovir is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Acyclovir may not be needed in these patients. Please consult your doctor.
Common questions
How to treat Herpes treatment sir?? Its came to me on sonta right side only, please help me sir Hello PATIENT a picture.Herpes simplex and herpes zoster r different and have different dosage Treatment of Herpes and precautions Herpes is of two types Herpes Simplex and Herpes Zooster. Treatment requires correct diagnosis. Let me know your symptoms and if you can send me the clinical findings of your Doctor Please suggest some medicines of canker sores or fever blister on mustache region Tablet or ointments etc. This is herpes labialisPlz visit for proper treatment meanwhile apply acivir gel twice a dayPlz visit for proper treatment I hv herpes blisters around lips and inside mouth ulcer any med to apply 6th day of course of medicine zovirax 800mg Tab Acivir 400 mg three times daily for 5 daysAcivir ointment once dailyFucidin cream once dailyTest : HSV 1 and 2 IGG and IGM Problems of Shingles/Herpes/ringworm on testicles and penis. Please send pictures to diagnose the condition properly Problem of Shingles/Herpes/ringworm on testicles and penis. Dear sir your problem can surely be treated with homeopathy but as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly. Beaded rashes on lips .lower buccal mucosa reddened with ulcers Can be an oral infection/herpes. Kindly consult dermatologist I have cold sores on lips every march this is 4th year Is there any cure or remedies for treating herpes simplex virus HI Kindly share your treatment detail